ArticlePloS one2014
Need for supplemental oxygen at discharge in infants with bronchopulmonary dysplasia is not associated with worse neurodevelopmental outcomes at 3 years corrected age.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association between Antenatal Antibiotic Exposure and Bronchopulmonary Dysplasia: A Systematic Review and Bayesian Model-Averaged Meta-Analysis.Neonatology · 2024Pooled it
- Tobacco Smoking During Pregnancy Is Associated With Increased Risk of Moderate/Severe Bronchopulmonary Dysplasia: A Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2020Pooled it
- Association of Chorioamnionitis With Bronchopulmonary Dysplasia Among Preterm Infants: A Systematic Review, Meta-analysis, and Metaregression.JAMA network open · 2019Pooled it
- Home oxygen use and 1-year outcome among preterm infants with bronchopulmonary dysplasia discharged from a Chinese regional NICU.Frontiers in pediatrics · 2022Article
- Predictors of Developmental and Respiratory Outcomes Among Preterm Infants With Bronchopulmonary Dysplasia.Frontiers in pediatrics · 2021Article
- Home Oxygen Use for Preterm Infants with Bronchopulmonary Dysplasia in California.The Journal of pediatrics · 2019Article
- Home Oxygen and 2-Year Outcomes of Preterm Infants With Bronchopulmonary Dysplasia.Pediatrics · 2019Article
- Bronchopulmonary dysplasia in very preterm infants: Outcome up to preschool age, in a single center of Austria.Pediatrics international : official journal of the Japan Pediatric Society · 2019Observational
- Serum neurotrophins at birth correlate with respiratory and neurodevelopmental outcomes of premature infants.Pediatric pulmonology · 2019Article
- Developmental outcomes of preterm infants with bronchopulmonary dysplasia-associated pulmonary hypertension at 18-24 months of corrected age.BMC pediatrics · 2019Article
- Fixel-based analysis of the preterm brain: Disentangling bundle-specific white matter microstructural and macrostructural changes in relation to clinical risk factors.NeuroImage. Clinical · 2019Article
- First-In-Human Administration of Allogeneic Amnion Cells in Premature Infants With Bronchopulmonary Dysplasia: A Safety Study.Stem cells translational medicine · 2018Article
- Twenty-four-hour in-house neonatologist coverage and long-term neurodevelopmental outcomes of preterm infants.Paediatrics & child health · 2017Article
- Attenuation of endoplasmic reticulum stress by caffeine ameliorates hyperoxia-induced lung injury.American journal of physiology. Lung cellular and molecular physiology · 2017Article
- Does chronic oxygen dependency in preterm infants with bronchopulmonary dysplasia at NICU discharge predict respiratory outcomes at 3 years of age?Journal of perinatology : official journal of the California Perinatal Association · 2015Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine if chronic oxygen dependency (discharge home on supplemental oxygen) in children with bronchopulmonary dysplasia (BPD; defined as requirement for supplemental O2 at 36 weeks postmenstrual age) predicts neurodevelopmental disability rates and growth outcomes at 36 months corrected age (CA). STUDY
designLongitudinal cohort study.
settingSouthern Alberta regional center located at high altitude.
participantsPreterm infants weighing ≤1250 grams with no BPD, BPD, and BPD with chronic oxygen dependency.
main outcome measuresNeurodevelopmental and growth outcomes.
resultsOf 1563 preterm infants admitted from 1995-2007, 1212 survived. Complete follow-up data were available for 1030 (85%) children. Children in BPD and BPD with chronic oxygen dependency groups had significantly lower birth weights, gestational ages, prolonged mechanical ventilation and oxygen supplementation and received more postnatal steroids, compared to those without BPD. Children with BPD and BPD with chronic oxygen dependency were more likely to be below the 5th centile in weight and height compared to those without BPD but there was little difference between the BPD and BPD with chronic oxygen dependency groups. After controlling for confounding variables, children who had BPD and BPD with chronic oxygen dependency had higher odds of neurodevelopmental disability compared to those without BPD [OR (odds ratio) 1.9 (95%CI 1.1 to 3.5) and OR 1.8 (1.1 to 2.9), respectively], with no significant difference between BPD and BPD with chronic oxygen dependency [OR 0.9 (95% CI 0.6 to 1.5)].
conclusionsBPD and BPD with chronic oxygen dependency in children predicts abnormal neurodevelopmental outcomes at 36 months CA. However, the neurodevelopmental disability rates were not significantly higher in BPD with chronic oxygen dependency children compared to children with BPD only. Compared to those without BPD, growth is impaired in children with BPD and BPD with chronic oxygen dependency, but no difference between the latter two groups.
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