ArticleBMC genomics2014
A pangenomic analysis of the Nannochloropsis organellar genomes reveals novel genetic variations in key metabolic genes.
Article in BMC genomics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed, 59 citations in OpenAlex.
- Insights into the Phylogeny and Enigmatic Mitochondrial Biology of Eustigmatophyte Algae From Over 50 Newly Sequenced Organellar Genomes.Genome biology and evolution · 2026Article
- Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 23: Suitability of taxonomic units notified to EFSA until September 2025.EFSA journal. European Food Safety Authority · 2026Article
- Best practices for methylome characterization in novel species: a case study in the microalgae Microchloropsis.Communications biology · 2025Article
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- Genome sequencing, assembly, and annotation of the self-flocculating microalga Scenedesmus obliquus AS-6-11.BMC genomics · 2020Article
- Identification of Eukaryotic Microalgal Strains.Journal of applied phycology · 2020Article
- Plastid Genomes and Proteins Illuminate the Evolution of Eustigmatophyte Algae and Their Bacterial Endosymbionts.Genome biology and evolution · 2019Article
- Advanced genetic tools enable synthetic biology in the oleaginous microalgae Nannochloropsis sp.Plant cell reports · 2018Review
- Complete Genome Sequence of the Model Oleaginous AlgaGenome announcements · 2018Article
- Plastid Genome of Dictyopteris divaricata (Dictyotales, Phaeophyceae): Understanding the Evolution of Plastid Genomes in Brown Algae.Marine biotechnology (New York, N.Y.) · 2017Article
- RNAi-mediated silencing of a pyruvate dehydrogenase kinase enhances triacylglycerol biosynthesis in the oleaginous marine alga Nannochloropsis salina.Scientific reports · 2017Article
- Conservation of core complex subunits shaped the structure and function of photosystem I in the secondary endosymbiont alga Nannochloropsis gaditana.The New phytologist · 2017Article
- Increased lipid production by heterologous expression of AtWRI1 transcription factor inBiotechnology for biofuels · 2017Article
- Characterization of the heterooligomeric red-type rubisco activase from red algae.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- The plastid genome of some eustigmatophyte algae harbours a bacteria-derived six-gene cluster for biosynthesis of a novel secondary metabolite.Open biology · 2016Article
- A Comparative Analysis of Mitochondrial Genomes in Eustigmatophyte Algae.Genome biology and evolution · 2016Article
- Heterologous overexpression of sfCherry fluorescent protein inBiotechnology reports (Amsterdam, Netherlands) · 2015Article
- Updating algal evolutionary relationships through plastid genome sequencing: did alveolate plastids emerge through endosymbiosis of an ochrophyte?Scientific reports · 2015Article
- Mutation rates in plastid genomes: they are lower than you might think.Genome biology and evolution · 2015Article
- The chloroplast genomes of Bryopsis plumosa and Tydemania expeditiones (Bryopsidales, Chlorophyta): compact genomes and genes of bacterial origin.BMC genomics · 2015Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicroalgae in the genus Nannochloropsis are photosynthetic marine Eustigmatophytes of significant interest to the bioenergy and aquaculture sectors due to their ability to efficiently accumulate biomass and lipids for utilization in renewable transportation fuels, aquaculture feed, and other useful bioproducts. To better understand the genetic complement that drives the metabolic processes of these organisms, we present the assembly and comparative pangenomic analysis of the chloroplast and mitochondrial genomes from Nannochloropsis salina CCMP1776.
resultsThe chloroplast and mitochondrial genomes of N. salina are 98.4% and 97% identical to their counterparts in Nannochloropsis gaditana. Comparison of the Nannochloropsis pangenome to other algae within and outside of the same phyla revealed regions of significant genetic divergence in key genes that encode proteins needed for regulation of branched chain amino synthesis (acetohydroxyacid synthase), carbon fixation (RuBisCO activase), energy conservation (ATP synthase), protein synthesis and homeostasis (Clp protease, ribosome).
conclusionsMany organellar gene modifications in Nannochloropsis are unique and deviate from conserved orthologs found across the tree of life. Implementation of secondary and tertiary structure prediction was crucial to functionally characterize many proteins and therefore should be implemented in automated annotation pipelines. The exceptional similarity of the N. salina and N. gaditana organellar genomes suggests that N. gaditana be reclassified as a strain of N. salina.
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