Evidence map›Paper›PMID 24646323›Full record

ArticlePlant biotechnology journal2014

Characterization of polyploid wheat genomic diversity using a high-density 90,000 single nucleotide polymorphism array.

Shichen Wang, Debbie Wong, Kerrie Forrest, Alexandra Allen, Shiaoman Chao, Bevan E Huang, Marco Maccaferri, Silvio Salvi, Sara G Milner, Luigi Cattivelli and 30 more

Abstract read
In one paragraph

Article in Plant biotechnology journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 975 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
975citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

975 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Fine mapping of QPm.caas-4BL.2 for adult-plant resistance to powdery mildew in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  14. Structural and coding variation inbioRxiv : the preprint server for biology · 2026
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  18. Genome-wide association mapping of native QTLs for Fusarium head blight resistance in US winter wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
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  20. Article

915 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors.

Shichen WangDepartment of Plant Pathology, Kansas State University, Manhattan, KS, USA.
Debbie Wong
Kerrie Forrest
Alexandra Allen
Shiaoman Chao
Bevan E Huang
Marco Maccaferri
Silvio Salvi
Sara G Milner
Luigi Cattivelli
Anna M Mastrangelo
Alex Whan
Stuart Stephen
Gary Barker
Ralf Wieseke
Joerg Plieske
International Wheat Genome Sequencing Consortium
Morten Lillemo
Diane Mather
Rudi Appels
Rudy Dolferus
Gina Brown-Guedira
Abraham Korol
Alina R Akhunova
Catherine Feuillet
Jerome Salse
Michele Morgante
Curtis Pozniak
Ming-Cheng Luo
Jan Dvorak
Matthew Morell
Jorge Dubcovsky
Martin Ganal
Roberto Tuberosa
Cindy Lawley
Ivan Mikoulitch
Colin Cavanagh
Keith J Edwards
Matthew Hayden
Eduard Akhunov

Funding

Biotechnology and Biological Sciences Research Council BB/E000126/1Biotechnology and Biological Sciences Research Council BB/E01268X/1Biotechnology and Biological Sciences Research Council BB/F001185/1Biotechnology and Biological Sciences Research Council BB/F010370/1Biotechnology and Biological Sciences Research Council BB/I003207/1Biotechnology and Biological Sciences Research Council BBS/B/01839Biotechnology and Biological Sciences Research Council BBS/B/02118Biotechnology and Biological Sciences Research Council BBS/B/07446Biotechnology and Biological Sciences Research Council EGA17701Howard Hughes Medical Institute
6 · The paper itself

Abstract

High-density single nucleotide polymorphism (SNP) genotyping arrays are a powerful tool for studying genomic patterns of diversity, inferring ancestral relationships between individuals in populations and studying marker-trait associations in mapping experiments. We developed a genotyping array including about 90,000 gene-associated SNPs and used it to characterize genetic variation in allohexaploid and allotetraploid wheat populations. The array includes a significant fraction of common genome-wide distributed SNPs that are represented in populations of diverse geographical origin. We used density-based spatial clustering algorithms to enable high-throughput genotype calling in complex data sets obtained for polyploid wheat. We show that these model-free clustering algorithms provide accurate genotype calling in the presence of multiple clusters including clusters with low signal intensity resulting from significant sequence divergence at the target SNP site or gene deletions. Assays that detect low-intensity clusters can provide insight into the distribution of presence-absence variation (PAV) in wheat populations. A total of 46 977 SNPs from the wheat 90K array were genetically mapped using a combination of eight mapping populations. The developed array and cluster identification algorithms provide an opportunity to infer detailed haplotype structure in polyploid wheat and will serve as an invaluable resource for diversity studies and investigating the genetic basis of trait variation in wheat.

Indexed as

Genetic VariationOligonucleotide Array Sequence AnalysisPolyploidyAllelesChromosome MappingCluster AnalysisGene FrequencyGenetic LociGenetic MarkersGenome, PlantGenotypePolymorphism, Single NucleotideTriticumGenetic Markersgenetic diversitygenotypinghigh-density mappolyploid wheatsingle nucleotide polymorphismwheat iSelect array

Identifiers

PMID24646323
PMCPMC4265271

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.