ReviewSkeletal radiology2014
T2* mapping for articular cartilage assessment: principles, current applications, and future prospects.
Review in Skeletal radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
54 citing papers in PubMed, 105 citations in OpenAlex.
- Compositional magnetic resonance imaging in the evaluation of the intervertebral disc: Axial vs sagittal TJournal of orthopaedic research : official publication of the Orthopaedic Research Society · 2020Trial
- A Clinical Study of Decellularized Tissue Engineering Hyaline Cartilage Graft (dLhCG) for Articular Cartilage Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Early intervertebral degeneration patterns among elite amateur golfers: A T2∗ mapping study.Brain & spine · 2026Article
- Magnetic resonance imaging of cruciate ligament disorders: current updates.EFORT open reviews · 2025Review
- A new four-area method for evaluating biochemical changes in lumbar facet joint degeneration on T2* mapping.BMC musculoskeletal disorders · 2025Article
- Sodium hyaluronate and acupotomy bone decompression alleviates inflammatory responses in patients with knee osteoarthritis.Inflammopharmacology · 2025Article
- Raman spectroscopic probe provides optical biomarkers of cartilage composition predictive of tissue function.Osteoarthritis and cartilage · 2025Article
- Beyond the Surface: Nutritional Interventions Integrated with Diagnostic Imaging Tools to Target and Preserve Cartilage Integrity: A Narrative Review.Biomedicines · 2025Review
- MRI monitoring of USPIO-labeled BMSCs combined with alginate scaffold for cartilage defect repair.Frontiers in bioengineering and biotechnology · 2025Article
- Primary anterior cruciate ligament repair-morphological and quantitative assessment by 7-T MRI and clinical outcome after 1.5 years.European radiology · 2024Article
- Assessment of the sacroiliac joint in patients with axial spondyloarthritis via three-dimensional ultrashort echo time magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2024Article
- Biochemical changes in lumbar facet joint and disc degeneration by T2* mapping.BMC musculoskeletal disorders · 2024Article
- Inflammatory activity evaluation in patients with axial spondyloarthritis using MRI relaxometry and mucosal-associated invariant T cells.Frontiers in immunology · 2024Article
- Variation in cartilage T2 and T2* mapping of the wrist: a comparison between 3- and 7-T MRI.European radiology experimental · 2023Article
- Updates on Compositional MRI Mapping of the Cartilage: Emerging Techniques and Applications.Journal of magnetic resonance imaging : JMRI · 2023Review
- Qualitative and Quantitative Evaluation of Morpho-Metabolic Changes in Bone Cartilage Complex of Knee Joint in Osteoarthritis Using Simultaneous 18F-NaF PET/MRI-A Pilot Study.The Indian journal of radiology & imaging · 2023Article
- T2*-Mapping of Knee Cartilage in Response to Mechanical Loading in Alpine Skiing: A Feasibility Study.Diagnostics (Basel, Switzerland) · 2022Article
- Patterns of Intervertebral Disk Alteration in Asymptomatic Elite Rowers: A T2* MRI Mapping Study.Orthopaedic journal of sports medicine · 2022Article
- High resolution T2∗ mapping in assessment of knee articular cartilage on 3T MRI.Journal of clinical orthopaedics and trauma · 2022Article
- Changes in T2 Relaxation Time Mapping of Intervertebral Discs Adjacent to Vertebrae after Kyphoplasty Correlate with the Physical Clinical Outcome of Patients.Diagnostics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With advances in joint preservation surgery that are intended to alter the course of osteoarthritis by early intervention, accurate and reliable assessment of the cartilage status is critical. Biochemically sensitive MRI techniques can add robust biomarkers for disease onset and progression, and therefore, could be meaningful assessment tools for the diagnosis and follow-up of cartilage abnormalities. T2* mapping could be a good alternative because it would combine the benefits of biochemical cartilage evaluation with remarkable features including short imaging time and the ability of high-resolution three-dimensional cartilage evaluation-without the need for contrast media administration or special hardware. Several in vitro and in vivo studies, which have elaborated on the potential of cartilage T2* assessment in various cartilage disease patterns and grades of degeneration, have been reported. However, much remains to be understood and certain unresolved questions have become apparent with these studies that are crucial to the further application of this technique. This review summarizes the principles of the technique and current applications of T2* mapping for articular cartilage assessment. Limitations of recent studies are discussed and the potential implications for patient care are presented.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.