Trial reportStroke2014
Translational neurorehabilitation research in the third world: what barriers to trial participation can teach us.
Trial report in Stroke, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01333579 (Low-frequency Transcranial Magnetic Stimulation To Enhance Motor Recovery In The Subacute Phase After Stroke), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Low-frequency Transcranial Magnetic Stimulation To Enhance Motor Recovery In The Subacute Phase After Stroke
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The willingness to participate in biomedical research involving human beings in low- and middle-income countries: a systematic review.Tropical medicine & international health : TM & IH · 2019Pooled it
- Barriers to patient recruitment in a poststroke neurorehabilitation multicenter trial in Brazil.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2023Trial
- Efficacy and safety of non-immersive virtual reality exercising in stroke rehabilitation (EVREST): a randomised, multicentre, single-blind, controlled trial.The Lancet. Neurology · 2016Trial
- Increase in Short-Interval Intracortical Facilitation of the Motor Cortex after Low-Frequency Repetitive Magnetic Stimulation of the Unaffected Hemisphere in the Subacute Phase after Stroke.Neural plasticity · 2015Trial
- Importance and Difficulties of Pursuing rTMS Research in Acute Stroke.Physical therapy · 2017Article
- Challenges in Recruitment for the Study of Noninvasive Brain Stimulation in Stroke: Lessons from Deep Brain Stimulation.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2016Article
- Upper Limb Immobilisation: A Neural Plasticity Model with Relevance to Poststroke Motor Rehabilitation.Neural plasticity · 2016Review
- A game of hide and seek: Is it possible to recruit more patients for NIBS studies in stroke?Journal of the neurological sciences · 2015Article
- Walking ability after stroke in patients from Argentina: predictive values of two tests in subjects with subacute hemiplegia.Journal of physical therapy science · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
background and purposeMost stroke rehabilitation studies have been performed in high-income countries. The aim of this study was to identify the main barriers for patient inclusion in a research protocol performed in Brazil.
methodsWe evaluated reasons for exclusion of patients in a pilot, randomized, double-blinded clinical trial of stroke rehabilitation. Descriptive statistical analysis was performed.
resultsOnly 5.6% of 571 screened patients were included. Recurrent stroke was responsible for exclusion of 45.4% of potentially eligible patients.
conclusionsRecurrent stroke represented a big barrier to enroll patients in the protocol. External validity of rehabilitation trials will benefit from definition of study criteria according to regional characteristics of patients, including rates of recurrent stroke. CLINICAL TRIAL REGISTRATION URL: http://www.clinicaltrials.gov. Unique identifier: NCT01333579.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.