ArticleThe Plant cell2014
WOX11 and 12 are involved in the first-step cell fate transition during de novo root organogenesis in Arabidopsis.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 257 papers.
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Who cites it
257 citing papers in PubMed.
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- EMF2 deficiency disrupts epigenetic and chromatin organization landscapes, blocking root regeneration competence in Arabidopsis.The New phytologist · 2026Article
- Genome-Wide Identification and Expression Analysis of theCurrent issues in molecular biology · 2026Article
- Newly found functions and regulatory networks of WOX family: what else does the WOX say?Planta · 2026Review
- Plant Regeneration: Influencing Factors, Regulatory Networks, and Epigenetic Mechanisms.International journal of molecular sciences · 2026Review
- SlGRF1 mediates gibberellin signaling to control cut-budding in tomato.Journal of integrative plant biology · 2026Article
- De novo stolon organogenesis in potato leaf callus elicited by Agrobacterium tumefaciens stimulus.Journal of integrative plant biology · 2026Article
- FERONIA defines intact tissue boundaries through cuticle development.Nature communications · 2026Article
- Stem cell activity is linked to a transient acquisition of pluripotency during callus proliferation.Nature communications · 2026Article
- A single-cell transcriptome atlas reveals the transcriptionally earliest state in rice callus.BMC plant biology · 2026Article
- PLETHORA-autophagy axis activates organ regeneration through ROS modulation.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Evolutionary history and functional diversification of WOX genes in Annona Atemoya.BMC plant biology · 2026Article
- Advances in the use of morphogenic regulators and peptide regenerating factors for boosting plant transformation and genome editing.Frontiers in plant science · 2026Review
- A novelFrontiers in plant science · 2026Article
- Genome-wide identification and characterization ofFrontiers in plant science · 2026Article
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- Proline transporters balance the salicylic acid-mediated trade-off between regeneration and immunity in plants.bioRxiv : the preprint server for biology · 2025Article
197 more citing papers are in PubMed but not listed here.
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
De novo organogenesis is a process through which wounded or detached plant tissues or organs regenerate adventitious roots and shoots. Plant hormones play key roles in de novo organogenesis, whereas the mechanism by which hormonal actions result in the first-step cell fate transition in the whole process is unknown. Using leaf explants of Arabidopsis thaliana, we show that the homeobox genes WUSCHEL RELATED HOMEOBOX11 (WOX11) and WOX12 are involved in de novo root organogenesis. WOX11 directly responds to a wounding-induced auxin maximum in and surrounding the procambium and acts redundantly with its homolog WOX12 to upregulate LATERAL ORGAN BOUNDARIES DOMAIN16 (LBD16) and LBD29, resulting in the first-step cell fate transition from a leaf procambium or its nearby parenchyma cell to a root founder cell. In addition, our results suggest that de novo root organogenesis and callus formation share a similar mechanism at initiation.
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