ArticleThe Plant cell2014
Linking gene expression and membrane lipid composition of Arabidopsis.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Remodeling of leaf lipidome during cold acclimation, de-acclimation, and re-acclimation influences frost tolerance of Festuca arundinacea.Plant & cell physiology · 2026Article
- Unraveling plankton adaptation in global oceans through the untargeted analysis of lipidomes.Science advances · 2025Article
- Phosphatidic acid produced by phospholipase Dα1 and Dδ is incorporated into the internal membranes but not involved in the gene expression ofFrontiers in plant science · 2024Article
- Transcriptome profiling of Bergenia purpurascens under cold stress.BMC genomics · 2023Article
- Hello darkness, my old friend: 3-KETOACYL-COENZYME A SYNTHASE4 is a branch point in the regulation of triacylglycerol synthesis in Arabidopsis thaliana.The Plant cell · 2023Article
- Lipidomics-Assisted GWAS (lGWAS) Approach for Improving High-Temperature Stress Tolerance of Crops.International journal of molecular sciences · 2022Review
- Identification and Transcriptome Analysis of Genes Related to Membrane Lipid Regulation in Sweet Sorghum under Salt Stress.International journal of molecular sciences · 2022Article
- TT2 controls rice thermotolerance through SCT1-dependent alteration of wax biosynthesis.Nature plants · 2022Article
- Integrated transcriptome and metabolome analyses revealed regulatory mechanisms of flavonoid biosynthesis inPeerJ · 2022Article
- Nonspecific phospholipase C4 hydrolyzes phosphosphingolipids and sustains plant root growth during phosphate deficiency.The Plant cell · 2021Article
- Chloroplast lipid biosynthesis is fine-tuned to thylakoid membrane remodeling during light acclimation.Plant physiology · 2021Article
- The Adjustment of Membrane Lipid Metabolism Pathways in Maize Roots Under Saline-Alkaline Stress.Frontiers in plant science · 2021Article
- The roles of chloroplast membrane lipids in abiotic stress responses.Plant signaling & behavior · 2020Article
- Analysis of wild tomato introgression lines elucidates the genetic basis of transcriptome and metabolome variation underlying fruit traits and pathogen response.Nature genetics · 2020Article
- Revealing Further Insights on Chilling Injury of Postharvest Bananas by Untargeted Lipidomics.Foods (Basel, Switzerland) · 2020Article
- Identification of Metabolite and Lipid Profiles in a Segregating Peach Population Associated with Mealiness inMetabolites · 2020Article
- The Role of Triacylglycerol in Plant Stress Response.Plants (Basel, Switzerland) · 2020Review
- The Wild Rice LocusFrontiers in plant science · 2020Article
- Combining transcriptomics and metabolomics to reveal the underlying molecular mechanism of ergosterol biosynthesis during the fruiting process of Flammulina velutipes.BMC genomics · 2019Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glycerolipid metabolism of plants responds dynamically to changes in light intensity and temperature, leading to the modification of membrane lipid composition to ensure optimal biochemical and physical properties in the new environment. Although multiple posttranscriptional regulatory mechanisms have been reported to be involved in the process, the contribution of transcriptional regulation remains largely unknown. Here, we present an integrative analysis of transcriptomic and lipidomic data, revealing large-scale coordination between gene expression and changes in glycerolipid levels during the Arabidopsis thaliana response to light and temperature stimuli. Using a multivariate regression technique called O2PLS, we show that the gene expression response is strictly coordinated at the biochemical pathway level and occurs in parallel with changes of specific glycerolipid pools. Five interesting candidate genes were chosen for further analysis from a larger set of candidates identified based on their close association with various groups of glycerolipids. Lipidomic analysis of knockout mutant lines of these five genes showed a significant relationship between the coordination of transcripts and glycerolipid levels in a changing environment and the effects of single gene perturbations.
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