ReviewHeredity2014
Supergenes and their role in evolution.
Review in Heredity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 191 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
191 citing papers in PubMed, 1 synthesis or guideline pooled it, 426 citations in OpenAlex.
- A cosmopolitan inversion facilitates seasonal adaptation in overwintering Drosophila.Genetics · 2024Pooled it
- Genome Evolution in Social Insects.Genome biology and evolution · 2026Review
- Polygenic and monogenic adaptation drive evolutionary rescue at different magnitudes of environmental change.The Journal of heredity · 2026Article
- Dual genetic loci and flavonoid metabolism orchestrate fruiting body coloration in Flammulina filiformis: a multi-omic roadmap for fungal pigmentation.Journal of advanced research · 2026Article
- Sequencing, annotation and analysis of the genome ofLife science alliance · 2026Article
- A T2T Genome of the Lobed-Lip Iguazu Joana (Crenicichla tuca) Reveals Intrachromosomal Rearrangements and Trans-species Polymorphism in Cichlid Fishes.Genome biology and evolution · 2026Article
- Phylogenomic blind spots: the limits of UCE and BUSCO loci in the presence of gene flow.Molecular biology and evolution · 2026Article
- Molecular Evolution of a Sex-Linked Inversion Polymorphism in Zebra Finches.Genome biology and evolution · 2026Article
- Distinct genomic architectures but the same gene underlie the convergent evolution of a plant supergene.Science advances · 2026Article
- Multiple Origins of a Sex Ratio Supergene in Formica Ants.Molecular biology and evolution · 2026Article
- Ancient but dynamic: structural expansion, massive gene duplication, and transposable element colonization in a supergene controlling ant social organization.Molecular biology and evolution · 2026Article
- Recombination suppression in plant adaptation and speciation.The New phytologist · 2026Review
- The Structure of the Chemotype Determining Locus inPlant direct · 2026Article
- Opposing behavioral roles for a single gene in a species with a supergene polymorphism.bioRxiv : the preprint server for biology · 2026Article
- Complex Patterns of Hitchhiking Mutation Load Among Stickleback Populations.Genome biology and evolution · 2026Article
- Article
- Introgression of barley chromosome arms 4H and 6H into wheat via Robertsonian translocations: GBS-assisted structural analysis and impact on grain nutrient composition.Plant molecular biology · 2026Article
- The evolutionary genomics of meiotic drive.Molecular biology and evolution · 2026Article
- Massive Genomic and Transcriptomic Changes Within a Young Inversion Polymorphism in the Absence of Degeneration.Molecular ecology · 2026Article
- Sex chromosome turnover and structural genome divergence shape meiotic outcomes in hybridizing Cobitis.GigaScience · 2026Article
131 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Adaptation is commonly a multidimensional problem, with changes in multiple traits required to match a complex environment. This is epitomized by balanced polymorphisms in which multiple phenotypes co-exist and are maintained in a population by a balance of selective forces. Consideration of such polymorphisms led to the concept of the supergene, where alternative phenotypes in a balanced polymorphism segregate as if controlled by a single genetic locus, resulting from tight genetic linkage between multiple functional loci. Recently, the molecular basis for several supergenes has been resolved. Thus, major chromosomal inversions have been shown to be associated with polymorphisms in butterflies, ants and birds, offering a mechanism for localised reduction in recombination. In several examples of plant self-incompatibility, the functional role of multiple elements within the supergene architecture has been demonstrated, conclusively showing that balanced polymorphism can be maintained at multiple coadapted and tightly linked elements. Despite recent criticism, we argue that the supergene concept remains relevant and is more testable than ever with modern molecular methods.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.