ReviewVirulence2014
Application of metagenomics in understanding oral health and disease.
Review in Virulence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 96 citations in OpenAlex.
- The Effect ofPolish journal of microbiology · 2020Trial
- Metagenomics in the Interplay Among Oral and Gut Dysbiosis.Metabolites · 2026Review
- Metagenomics as an Effective Diagnostic Approach for Exploring Oral Microbial Diversity and Dental Diseases: A Narrative Review.International journal of clinical pediatric dentistry · 2026Review
- Multi-Omics Insights into Gingivitis from a Clinical Trial: Understanding the Role of Bacterial and Host Factors.Microorganisms · 2025Article
- Effect of medicated toothpastes and Tooth Mousse on cariogenic microbes of the oral cavity: AnJournal of conservative dentistry and endodontics · 2024Article
- The Evolving Microbiome of Dental Caries.Microorganisms · 2024Review
- Review
- Leveraging genomic signatures of oral microbiome-associated antibiotic resistance genes for diagnosing pancreatic cancer.PloS one · 2024Article
- Oral Microbiome Traits of Type 1 Diabetes and Phenylketonuria Patients in Latvia.Microorganisms · 2023Article
- Unraveling the impact of primary immunodeficiency disorders on the microbiota of dental caries in children through 16S rRNA gene-based metagenomic analysis.Turkish journal of medical sciences · 2023Article
- Polymicrobial Infections and Biofilms: Clinical Significance and Eradication Strategies.Antibiotics (Basel, Switzerland) · 2022Review
- An extensive description of the microbiological effects of silver diamine fluoride on dental biofilms using an oral in situ model.Scientific reports · 2022Article
- Annotated protein network analysis linking oral diseases.Bioinformation · 2022Article
- The oral microbiome and salivary proteins influence caries in children aged 6 to 8 years.BMC oral health · 2020Article
- The Subgingival Microbiome in Patients with Down Syndrome and Periodontitis.Journal of clinical medicine · 2020Article
- Metagenomic investigation of bacteria associated with dental lesions: a cross-sectional study.Medicina oral, patologia oral y cirugia bucal · 2020Article
- Consumer Safety Considerations of Skin and Oral Microbiome Perturbation.Clinical microbiology reviews · 2019Review
- A Literature Review of Metagenomics and Culturomics of the Peri-implant Microbiome: Current Evidence and Future Perspectives.Materials (Basel, Switzerland) · 2019Review
- Establishment of Integrated Biobank for Precision Medicine and Personalized Healthcare: The Tohoku Medical Megabank Project.JMA journal · 2019Article
- The microbiota of the mother at birth and its influence on the emerging infant oral microbiota from birth to 1 year of age: a cohort study.Journal of oral microbiology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Oral diseases including periodontal disease and caries are some of the most prevalent infectious diseases in humans. Different microbial species cohabitate and form a polymicrobial biofilm called dental plaque in the oral cavity. Metagenomics using next generation sequencing technologies has produced bacterial profiles and genomic profiles to study the relationships between microbial diversity, genetic variation, and oral diseases. Several oral metagenomic studies have examined the oral microbiome of periodontal disease and caries. Gene annotations in these studies support the association of specific genes or metabolic pathways with oral health and with specific diseases. The roles of pathogenic species and functions of specific genes in oral disease development have been recognized by metagenomic analysis. A model is proposed in which three levels of interactions occur in the oral microbiome that determines oral health or disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.