Evidence map›Paper›PMID 24642475›Full record

ArticleGut microbes

The gastric microbial community, Helicobacter pylori colonization, and disease.

Miriam E Martin, Jay V Solnick

Open access · bronzeAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. The association of the advanced lung cancer inflammation index with the risk ofFrontiers in cellular and infection microbiology · 2026
    Article
  3. Global Trend on Machine Learning inGlobal health, epidemiology and genomics · 2023
    Article
  4. Article
  5. The interactions between oral-gut axis microbiota andFrontiers in cellular and infection microbiology · 2022
    Review
  6. Curcumin Oxidation Is Required for Inhibition ofFrontiers in cellular and infection microbiology · 2021
    Article
  7. The Exopolysaccharide ofMicroorganisms · 2020
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Miriam E MartinDepartment of Medicine; University of California-Davis; Davis, CA USA; Department of Microbiology & Immunology; University of California-Davis; Davis, CA USA.
Jay V SolnickDepartment of Medicine; University of California-Davis; Davis, CA USA; Department of Microbiology & Immunology; University of California-Davis; Davis, CA USA; California National Primate Research Center; University of California-Davis; Davis, CA USA.
Oregon National Primate Research Center · USUniversity of California, Davis · US

Funding

Modulation of Outer Membrane Protein Expressin in Helicobacter pyloriR01AI070803 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SOLNICK, JAY V. · 2008 to 2012
$2.4M
Serum biomarkers for early detection of H. pylori-associated gastric cancerR01CA136647 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SOLNICK, JAY V. · 2009 to 2013
$1.5M
Role of H. pylori Outer Membrane Proteins in Colonization and Host ResponseR01AI081037 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SOLNICK, JAY V. · 2009 to 2013
$1.1M
Helicobacter pylori and the gastric microbial community in rhesus macaquesR21AI080788 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI SOLNICK, JAY V. · 2009 to 2010
$421k
NCI NIH HHS CA136647NCI NIH HHS R01 CA136647NIAID NIH HHS AI070803NIAID NIH HHS AI080788NIAID NIH HHS AI081037NIAID NIH HHS R01 AI070803NIAID NIH HHS R01 AI081037NIAID NIH HHS R21 AI080788
6 · The paper itself

Abstract

Long thought to be a sterile habitat, the stomach contains a diverse and unique community of bacteria. One particular inhabitant, Helicobacter pylori, colonizes half of the world's human population and establishes a decades-long infection that can be asymptomatic, pathogenic, or even beneficial for the host. Many host and bacterial factors are known to influence an individual's risk of gastric disease, but another potentially important determinant has recently come to light: the host microbiota. Although it is unclear to what extent H. pylori infection perturbs the established gastric microbial community, and H. pylori colonization seems generally resistant to disturbances in the host microbiota, it can modulate H. pylori pathogenicity. Interactions between H. pylori and bacteria at non-gastric sites are likely indirect--via programming of the pro-inflammatory vs. regulatory T lymphocytes--which may have a significant impact on human health.

Indexed as

BiotaMicrobial InteractionsAnimalsDisease Models, AnimalGastric MucosaHelicobacter InfectionsHelicobacter pyloriHumansMacaca mulatta16S rDNAdiseaseHelicobacter pylorihumanmicrobial communitymicrobiotamouserhesus monkeystomach

Identifiers

PMID24642475
PMCPMC4153772
OpenAlexW1970997744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.