Evidence map›Paper›PMID 24641995›Full record

ArticleTrends in microbiology2014

Long-lived reservoirs of HIV-1.

Thomas D Zaikos, Kathleen L Collins

Abstract readComment
In one paragraph

Article in Trends in microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Current approaches to HIV vaccine development: a narrative review.Journal of the International AIDS Society · 2021
    Review
  2. Article
  3. Article
  4. Review
  5. Broad Spectrum Mixed Lineage Kinase Type 3 Inhibition and HIV-1 Persistence in Macrophages.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2019
    Review
  6. Review
  7. Review
  8. Bioinformatics and HIV latency.Current HIV/AIDS reports · 2015
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Thomas D ZaikosDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA.
Kathleen L CollinsDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. Electronic address: klcollins@umich.edu.
University of Michigan–Ann Arbor · US

Funding

HIV Infection of Hematopoietic Progenitor CellsR01AI096962 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 2012 to 2016
$2.9M
NIAID NIH HHS R01 AI096962
6 · The paper itself

Abstract

HIV-1 persistence in long-lived cellular reservoirs remains a major barrier to a cure. In a recent Nature Medicine paper, Buzon et al. identify memory T cells with stem cell-like properties (TSCM) that harbor infectious provirus and that likely contribute to HIV-1 persistence.

Indexed as

PhylogenyVirus LatencyCD4-Positive T-LymphocytesDisease ReservoirsHIV-1HIV InfectionsHumansLymphoid Progenitor Cells

Identifiers

PMID24641995
PMCPMC4048589
OpenAlexW2056441907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.