ArticlePain management2014
A practical guide and perspectives on the use of experimental pain modalities with children and adolescents.
Article in Pain management, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04031716 (Genetic, Epigenetic, Psychosocial, and Biological Determinants of Post-surgical Pain After Pectus or Spine Surgery), which is not on this map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Genetic, Epigenetic, Psychosocial, and Biological Determinants of Post-surgical Pain After Pectus or Spine Surgery
Who cites it
19 citing papers in PubMed, 55 citations in OpenAlex.
- Painfully Sensitive: How Sensory Processing Sensitivity Affects Healthy Adolescents' Perception of Pain.Journal of pain research · 2025Article
- A Systematic Review and Meta-Analysis of Conditioned Pain Modulation in Children and Young People with Chronic Pain.Children (Basel, Switzerland) · 2024Review
- Advancing Pain Understanding and Drug Discovery: Insights from Preclinical Models and Recent Research Findings.Pharmaceuticals (Basel, Switzerland) · 2024Review
- Pain Catastrophizing Moderates the Relationship Between Pain Sensitivity and Clinical Pain in Adolescents With Functional Abdominal Pain.The journal of pain · 2024Article
- Quantitative sensory testing for assessment of somatosensory function in children and adolescents: a scoping review.Pain reports · 2024Article
- Denver pain authenticity stimulus set (D-PASS).Behavior research methods · 2024Article
- Central sensitization in adolescents with hypermobility spectrum disorder or hypermobile Ehlers-Danlos syndrome-a feasibility study.Pilot and feasibility studies · 2023Article
- Analysis of Physiological Responses during Pain Induction.Sensors (Basel, Switzerland) · 2022Article
- Alterations in pain processing circuitries in episodic migraine.The journal of headache and pain · 2022Article
- Attenuating Pain With the Past: Nostalgia Reduces Physical Pain.Frontiers in psychology · 2020Article
- Youth and Parent Appraisals of Participation in a Study of Spontaneous and Induced Pediatric Clinical Pain.Ethics & behavior · 2019Article
- Pain and executive functions: a unique relationship between Stroop task and experimentally induced pain.Psychological research · 2018Article
- A scoping review on the study of siblings in pediatric pain.Canadian journal of pain = Revue canadienne de la douleur · 2017Article
- Current methodological approaches in conditioned pain modulation assessment in pediatrics.Journal of pain research · 2017Review
- A Multi-Informant Multi-Method Investigation of Family Functioning and Parent-Child Coping During Children's Acute Pain.Journal of pediatric psychology · 2017Article
- Association Between Widespread Pain Scores and Functional Impairment and Health-Related Quality of Life in Clinical Samples of Children.The journal of pain · 2016Article
- Persistent changes in peripheral and spinal nociceptive processing after early tissue injury.Experimental neurology · 2016Review
- Pain Response after Maximal Aerobic Exercise in Adolescents across Weight Status.Medicine and science in sports and exercise · 2015Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Use of experimental pain is vital for addressing research questions that would otherwise be impossible to examine in the real world. Experimental induction of pain in children is highly scrutinized given the potential for harm and lack of direct benefit to a vulnerable population. However, its use has critically advanced our understanding of the mechanisms, assessment and treatment of pain in both healthy and chronically ill children. This article introduces various experimental pain modalities, including the cold pressor task, the water load symptom provocation test, thermal pain, pressure pain and conditioned pain modulation, and discusses their application for use with children and adolescents. It addresses practical implementation and ethical issues, as well as the advantages and disadvantages offered by each task. The incredible potential for future research is discussed given the array of experimental pain modalities now available to pediatric researchers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.