ArticleThe British journal of radiology2014
Imaging features of primary and metastatic alveolar soft part sarcoma: single institute experience in 25 patients.
Article in The British journal of radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Guideline
- Primary Intracranial Alveolar Soft Part Sarcoma: Systematic Review.Pakistan journal of medical sciences · 2025Review
- Qualitative and quantitative MRI analysis of alveolar soft part sarcoma: correlation with histological grade and Ki-67 expression.Insights into imaging · 2024Article
- Brain metastases of sarcoma: a rare phenomenon in rare tumours.Journal of cancer research and clinical oncology · 2023Review
- Imaging Features of Alveolar Soft Part Sarcoma: Single Institution Experience and Literature Review.Clinics and practice · 2023Article
- Alveolar soft part sarcoma of the superior rectus muscle: Case report and review of literature.American journal of ophthalmology case reports · 2022Article
- Alveolar soft part sarcoma of the orbit: A case report.Radiology case reports · 2021Article
- Primary Alveolar Soft Part Sarcoma of Cheek: Report of a Case and Review of the Literature.Head and neck pathology · 2021Review
- Imaging and Pathological Features of Alveolar Soft Part Sarcoma: Analysis of 16 Patients.The Indian journal of radiology & imaging · 2021Article
- iCREATE: imaging features of primary and metastatic alveolar soft part sarcoma from the EORTC CREATE study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2020Article
- Computed tomography, magnetic resonance imaging, and F-deoxyglucose positron emission computed tomography/computed tomography findings of alveolar soft part sarcoma with calcification in the thigh: A case report.World journal of clinical cases · 2020Article
- Ultrasonography of Pediatric Superficial Soft Tissue Tumors and Tumor-Like Lesions.Korean journal of radiology · 2020Review
- Soft Tissue Special Issue: Imaging of Bone and Soft Tissue Sarcomas in the Head and Neck.Head and neck pathology · 2020Review
- Alveolar soft-part sarcoma: can MRI help discriminating from other soft-tissue tumors? A study of the French sarcoma group.European radiology · 2019Article
- Exploring the Histogenesis and Diagnostic Strategy Using Immunoassay and RT-PCR in Alveolar Soft Part Sarcoma.Pathology oncology research : POR · 2018Article
- Brain metastatic alveolar soft-part sarcoma: Clinicopathological profiles, management and outcomes.Oncology letters · 2017Article
- Identification of target genes of cediranib in alveolar soft part sarcoma using a gene microarray.Oncology letters · 2017Article
- Surgical management and outcome of spinal alveolar soft part sarcoma (ASPA): a case series of five patients and literature review.World journal of surgical oncology · 2017Review
- A retrospective analysis of lung metastasis in 64 patients with alveolar soft part sarcoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2015Article
- Imaging features of primary and metastatic extremity synovial sarcoma: a single institute experience of 78 patients.The British journal of radiology · 2015Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe imaging features of primary and metastatic alveolar soft part sarcoma (ASPS).
methodsIn this institutional review board-approved and Health Insurance Portability and Accountability Act-compliant retrospective study, 25 patients (14 males; mean age, 25 years; range, 18-40 years) with pathologically proven ASPS seen at our institute between 1995 and 2013 were included. Imaging of primary tumours in 5 patients and follow-up imaging in 25 patients were reviewed by 2 radiologists in consensus. Clinical information was obtained from electronic medical records.
resultsThe most common sites for the primary tumour were extremities (17/25, 68%) and torso (6/25, 24%). Primary tumours (n = 5) were well circumscribed, compared with skeletal muscle, were isodense on CT, hyperintense on T1 and T2 weighted images with intense post-contrast enhancement, prominent feeders on CT and flow voids on MRI. Metastases developed in 23/25 (92%) patients, 18 at presentation. The most common sites of metastases were the lungs (100%), lymph nodes (74%), bones (57%) and brain (43%). Visceral and nodal metastases were hypervascular. At the time of reporting the results, 15 patients have died, 6 are alive and 4 were lost to follow-up. Median survival was 74 months for those without brain metastases (n = 8) and 60 months for those with brain metastases (n = 7). Median survival was shorter for patients with metastases at presentation.
conclusionASPS most commonly involves the lower extremities of young adults, is hypervascular on imaging, often metastasizes at presentation, frequently to lung, nodes, bones and brain, and has an indolent course despite metastases. Brain metastases and high tumour burden (number of metastatic sites) at presentation decreased survival in our study. ADVANCES IN KNOWLEDGE: ASPS has an unusual pattern of metastases to the brain and nodes in addition to lung and bones. It has an indolent course despite metastases.
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