ArticleJournal of clinical hypertension (Greenwich, Conn.)2014
Association of serum osteoprotegerin levels with carotid-femoral pulse wave velocity in hypertensive patients.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Serum Osteoprotegerin Is Associated Independently with Peripheral Arterial Stiffness in Chronic Kidney Disease.Diagnostics (Basel, Switzerland) · 2026Article
- Serum Osteoprotegerin and Carotid Intima-Media Thickness Are Related to High Arterial Stiffness in Heart Failure with Reduced Ejection Fraction.Diagnostics (Basel, Switzerland) · 2021Article
- Association of Low Serum l-Carnitine Levels with Aortic Stiffness in Patients with Non-Dialysis Chronic Kidney Disease.Nutrients · 2020Article
- Serum Malondialdehyde-Modified Low-Density Lipoprotein Is a Risk Factor for Central Arterial Stiffness in Maintenance Hemodialysis Patients.Nutrients · 2020Article
- Serum Sclerostin But Not DKK-1 Correlated with Central Arterial Stiffness in End Stage Renal Disease Patients.International journal of environmental research and public health · 2020Article
- SerumToxins · 2019Article
- Serum osteoprotegerin is an independent marker of central arterial stiffness as assessed using carotid-femoral pulse wave velocity in hemodialysis patients: a cross sectional study.BMC nephrology · 2019Article
- The Role of Osteoprotegerin as a Cardioprotective Versus Reactive Inflammatory Marker: the Chicken or the Egg ParadoxBalkan medical journal · 2018Review
- Hyperleptinemia positively associated with central arterial stiffness in hemodialysis patients.PloS one · 2018Article
- Circulating miR-92a expression level in patients with essential hypertension: a potential marker of atherosclerosis.Journal of human hypertension · 2017Article
- Article
- Serum resistin as an independent marker of aortic stiffness in patients with coronary artery disease.PloS one · 2017Article
- Association of serum leptin levels with central arterial stiffness in coronary artery disease patients.BMC cardiovascular disorders · 2016Article
- Positive correlation of serum adipocyte fatty acid binding protein levels with carotid-femoral pulse wave velocity in geriatric population.BMC geriatrics · 2015Article
- Serum osteopontin level correlates with carotid-femoral pulse wave velocity in geriatric persons.BioMed research international · 2014Article
- Serum osteoprotegerin levels associated with the aortic augmentation index in renal transplant recipients.Tzu chi medical journalArticle
- Osteocalcin and carotid-femoral pulse wave velocity in patients on peritoneal dialysis.Tzu chi medical journalArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoprotegerin (OPG) has been implicated in the process of vascular stiffness. The aim of this study was to evaluate the relationship between fasting serum OPG concentration and carotid-femoral pulse wave velocity (c-f PWV) in hypertensive patients. Fasting blood samples were obtained from 184 participants with or without hypertension. c-f PWV were performed by SphygmoCor system. Serum OPG levels were measured using a commercially available enzyme-linked immunosorbent assay. Hypertensive patients who had diabetes had higher c-f PWV levels than those without diabetes (P=.031). The univariable linear regression analysis showed that age (P<.001), systolic blood pressure (P=.003), pulse pressure (r=0.287; P=.003), log-BUN (P=.011), Cre (P<.001), and log-OPG concentration (P<.001) were positively correlated with c-f PWV levels, while the glomerular filtration rate (P=.005) and HDL-C level (P=.024) was negatively correlated with c-f PWV levels among the hypertensive patients. Multivariable forward stepwise linear regression analysis of the significant variables also showed that log-OPG (β=0.312, regression coefficient: 1.736; 95% confidence interval, 0.809-2.663; P<.001) was still an independent predictor of c-f PWV levels in hypertensive patients. Serum OPG levels positively associated with c-f PWV levels in hypertensive patients.
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