ArticleInternational journal of vascular medicine2014
Investigation of serum oxidized low-density lipoprotein IgG levels in patients with angiographically defined coronary artery disease.
Article in International journal of vascular medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Safety and Efficacy of Simultaneous Inoculations of Pneumococcal and Influenza Vaccines in Patients with Coronary Artery Disease.Journal of atherosclerosis and thrombosis · 2021Trial
- The Dual Role of Oxidative Stress in Atherosclerosis and Coronary Artery Disease: Pathological Mechanisms and Diagnostic Potential.Antioxidants (Basel, Switzerland) · 2025Review
- Acute effect of proprotein convertase subtilisin/kexin type 9 inhibitor on oxidized low-density lipoprotein and lipid profile in patients at cardiovascular risk.Journal of clinical biochemistry and nutrition · 2023Article
- Over-expression of IL1R2 in PBMCs of Patients with Coronary Artery Disease and Its Clinical Significance.Anatolian journal of cardiology · 2022Article
- Anti-Oxidized LDL Antibodies and Coronary Artery Disease: A Systematic Review.Antioxidants (Basel, Switzerland) · 2019Review
- Associations between circulating IgG antibodies to Apolipoprotein BBioscience reports · 2018Article
- The association between oxidized low-density lipoprotein antibodies and hematological diseases.Lipids in health and disease · 2016Article
- Is the Ratio of Antibodies Against Oxidized LDL to Oxidized LDL an Indicator of Cardiovascular Risk in Psoriasis?Oman medical journal · 2016Article
- Fcγ receptors and ligands and cardiovascular disease.Circulation research · 2015Review
- Roles of antibody against oxygenized low density lipoprotein in atherosclerosis: recent advances.International journal of clinical and experimental medicine · 2015Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been suggested that antioxidized low-density lipoprotein (anti-oxLDL) antibodies play a role in the pathogenesis of atherosclerosis. The aim of this study was to measure serum ox-LDL IgG levels in 31 patients with angiographically defined coronary artery disease (CAD) (≥50% stenosis in at least one major coronary artery; CAD(+) group) and compare these levels with those of 32 subjects with <50% coronary stenosis (CAD(-) group) and 24 healthy age- and sex-matched controls using ELISA. We did not find any significant difference between CAD(+), CAD(-), and control groups in regard to oxLDL IgG levels (P = 0.83). Serum oxLDL IgG levels did not differ between 1VD (one vessel disease), 2VD (2 vessels disease), and 3VD (3 vessels disease) subgroups of CAD(+) patients (P = 0.20). Serum anti-oxLDL titers were only significantly correlated with LDL-C in the CAD(+) group (P < 0.05) and waist and hip circumference (P < 0.05 and P < 0.01, resp.) in the CAD(-) group. In stepwise regression analysis, none of the conventional cardiovascular risk factors was associated with serum ox-LDL IgG levels. The present results suggest that serum levels of ox-LDL IgG are neither associated with the presence and severity of CAD nor with the conventional cardiovascular risk factors.
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Registered trials
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