Evidence map›Paper›PMID 24639849›Full record

ArticlePakistan journal of medical sciences2014

Preoperative serum tumor marker levels in gastric cancer.

Erdal Polat, Ugur Duman, Mustafa Duman, Kivanc Derya Peker, Cebrail Akyuz, Necdet Fatih Yasar, Orhan Uzun, Sabiye Akbulut, Erdal Birol Bostanci, Sinan Yol

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pakistan journal of medical sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Erdal PolatErdal Polat, MD, Department of Gastrointestinal Surgery, Kosuyolu High Specialty Training and Research Hospital, Istanbul, Turkey.
Ugur DumanUgur Duman, MD, Bursa Sevket Yilmaz Training and Research Hospital, Department of General Surgery, Bursa, Turkey.
Mustafa DumanMustafa Duman, MD, Associate Professor, Department of Gastrointestinal Surgery, Kosuyolu High Specialty Training and Research Hospital, Istanbul, Turkey.
Kivanc Derya PekerKivanc Derya Peker, MD, Department of Gastrointestinal Surgery, Kosuyolu High Specialty Training and Research Hospital, Istanbul, Turkey.
Cebrail AkyuzCebrail Akyuz, MD, Department of Gastrointestinal Surgery, Kosuyolu High Specialty Training and Research Hospital, Istanbul, Turkey.
Necdet Fatih YasarNecdet Fatih Yasar, MD, Department of Gastrointestinal Surgery, Kosuyolu High Specialty Training and Research Hospital, Istanbul, Turkey.
Orhan UzunOrhan Uzun, MD, Department of Gastrointestinal Surgery, Kosuyolu High Specialty Training and Research Hospital, Istanbul, Turkey.
Sabiye AkbulutSabiye Akbulut, MD, Department of Gastroenterology, Kosuyolu High Specialty Training and Research Hospital, Istanbul, Turkey.
Erdal Birol BostanciErdal Birol Bostanci, MD, Professor, Department of Gastrointestinal Surgery, Turkiye High Specialty Training and Research Hospital, Ankara, Turkey.
Sinan YolSinan Yol, MD, Professor, Department of Gastrointestinal Surgery, Kosuyolu High Specialty Training and Research Hospital, Istanbul, Turkey.
Kartal Koşuyolu High Specialization Training and Research Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTumor markers have shown little benefit as a method for screening. However, they can be used clinically for the monitoring of tumor recurrence and used as prognostic factors because higher levels have been observed in advanced disease. This study aimed to investigate the relationship between the preoperative tumor marker levels and different clinical aspects of gastric cancer.

methodsOne hundred and six consecutive patients with confirmed diagnosis of gastric cancer and 106 subjects (age and sex matched) with no malignancy as control group were included prospectively in this study in 3 years. The relationships between tumor markers CEA, CA 19-9 and stage of disease, tumor differentiation, presence of ringlet cell type, presence of peritoneal carcinomatozis were investigated.

resultsThe serum CEA and CA 125 levels were found to be significantly elevated in gastric cancer patients than in controls. The serum level of CEA had showed a significant elevation with the presence of distant metastasis. The CA 19-9 and CA 125 levels had showed significant elevations with the presence of peritoneal carcinomatozis. Conclusions : This study showed that there is a limited clinical benefit of preoperative tumor marker measurements in gastric cancer such as estimation of peritoneal dissemination.

Indexed as

Gastric cancerPeritoneal carcinomatozisSerum tumor markers

Identifiers

PMID24639849
PMCPMC3955560
OpenAlexW2146055626

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.