Evidence map›Paper›PMID 24639804›Full record

ArticleIranian journal of reproductive medicine2013

Identification of Xq22.1-23 as a region linked with hereditary recurrent spontaneous abortion in a family.

Sahar Shekouhi, Fatemeh Baghbani, Mohammad Hasanzadeh Nazar-Abadi, Tayebeh Hamzehloie, Mohammad Reza Abbaszadegan, Nafiseh Saghafi, Reza Raoofian, Javad Zavar Reza, Shahab Ahmadzadeh, Mohammad Amin Tabatabaiefar and 1 more

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Article in Iranian journal of reproductive medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Sahar ShekouhiDepartment of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Fatemeh BaghbaniDepartment of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Hasanzadeh Nazar-AbadiDepartment of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Tayebeh HamzehloieDepartment of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Reza AbbaszadeganDepartment of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Nafiseh SaghafiDepartment of Gynecology, Qaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Reza RaoofianDepartment of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Javad Zavar RezaDepartment of Biochemistry, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Shahab AhmadzadehDepartment of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Amin TabatabaiefarDepartment of Medical Genetics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Majid MojarradDepartment of Medical Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IRAhvaz Jundishapur University of Medical Sciences · IRShahid Sadoughi University of Medical Sciences and Health Services · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecurrent spontaneous abortion (RSA) is one of the most common health complications with a strong genetic component. Several genetic disorders were identified as etiological factors of hereditary X linked RSA. However, more genetic factors remain to be identified.

objectiveIn this study we performed linkage analysis on a large X linked RSA pedigree to find a novel susceptibility locus for RSA. MATERIALS AND

methodsA linkage scan using 11 microsatellites was performed in 27 members of a large pedigree of hereditary X-linked RSA. Two point parametric Linkage was performed using Superlink v 1.6 program.

resultsEvidence of linkage was observed to markers at Xq23, DXS7133 and at Xq22.1 DXS101, with LOD score of 3.12 and 1.60, respectively.

conclusionIdentified locus in this study may carry a responsible gene in RSA. Narrowing down of this region may leads to identification of this gene. This article extracted from M.Sc. thesis. (Sahar Shekouhi).

Indexed as

LinkageRecurrentspontaneousabortionX-linked

Identifiers

PMID24639804
PMCPMC3941371
OpenAlexW87991605

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