ReviewFrontiers in plant science2014
Phenotypic and molecular consequences of overexpression of metal-homeostasis genes.
Review in Frontiers in plant science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 44 citations in OpenAlex.
- Zinc translocation from Zn-sufficient to Zn-deficient roots as an adaptation to heterogeneous Zn availability.BMC plant biology · 2025Article
- Tobacco as an efficient metal accumulator.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2023Review
- The ethylene-responsive transcription factor of durum wheat, TdSHN1, confers cadmium, copper, and zinc tolerance to yeast and transgenic tobacco plants.Protoplasma · 2022Article
- Genome wide search to identify reference genes candidates for gene expression analysis in Gossypium hirsutum.BMC plant biology · 2019Article
- Dual Role of Metallic Trace Elements in Stress Biology-From Negative to Beneficial Impact on Plants.International journal of molecular sciences · 2019Review
- Functional Analysis ofFrontiers in plant science · 2018Article
- The ratio of Zn to Cd supply as a determinant of metal-homeostasis gene expression in tobacco and its modulation by overexpressing the metal exporter AtHMA4.Journal of experimental botany · 2016Article
- Engineering high Zn in tomato shoots through expression of AtHMA4 involves tissue-specific modification of endogenous genes.BMC genomics · 2016Article
- Synonymous mutation gene design to overexpress ACCase in creeping bentgrass to obtain resistance to ACCase-inhibiting herbicides.Transgenic research · 2016Article
- NOD promoter-controlled AtIRT1 expression functions synergistically with NAS and FERRITIN genes to increase iron in rice grains.Plant molecular biology · 2016Article
- Characterization of Zinc and Cadmium Hyperaccumulation in Three Noccaea (Brassicaceae) Populations from Non-metalliferous Sites in the Eastern Pyrenees.Frontiers in plant science · 2016Article
- Functional analysis of the three HMA4 copies of the metal hyperaccumulator Arabidopsis halleri.Journal of experimental botany · 2015Article
- Target or barrier? The cell wall of early- and later-diverging plants vs cadmium toxicity: differences in the response mechanisms.Frontiers in plant science · 2015Article
- Determination the Usefulness ofWater, air, and soil pollutionArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metal hyperaccumulating plants are able to store very large amounts of metals in their shoots. There are a number of reasons why it is important to be able to introduce metal hyperaccumulation traits into non-accumulating species (e.g., phytoremediation or biofortification in minerals) and to engineer a desired level of accumulation and distribution of metals. Metal homeostasis genes have therefore been used for these purposes. Engineered accumulation levels, however, have often been far from expected, and transgenic plants frequently display phenotypic features not related to the physiological function of the introduced gene. In this review, we focus on an aspect often neglected in research on plants expressing metal homeostasis genes: the specific regulation of endogenous metal homeostasis genes of the host plant in response to the transgene-induced imbalance of the metal status. These modifications constitute one of the major mechanisms involved in the generation of the plant's phenotype, including unexpected characteristics. Interestingly, activation of so-called "metal cross-homeostasis" has emerged as a factor of primary importance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.