Evidence map›Paper›PMID 24639613›Full record

ArticleThe Malaysian journal of medical sciences : MJMS2014

Correlation of common biochemical markers for bone turnover, serum calcium, and alkaline phosphatase in post-menopausal women.

Tirtha Bhattarai, Koushik Bhattacharya, Prasenjit Chaudhuri, Pallav Sengupta

Abstract read
In one paragraph

Article in The Malaysian journal of medical sciences : MJMS, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Prevalence of low bone mineral density in inflammatory bowel disease and factors associated with it.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2020
    Article
  15. Effect of herbal extract Eurycoma longifolia (PhystaBMC complementary medicine and therapies · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tirtha BhattaraiDepartment of Community Health, Everest Nursing College, Nepal, Pincode 44600, India.
Koushik BhattacharyaDepartment of Physiology, Vidyasagar College for Women, University of Calcutta, Kolkata, Pincode 700006, West Bengal, India.
Prasenjit ChaudhuriDepartment of Physiology, Sonarpur Mahavidyalaya, University of Calcutta, Kolkata, Pincode 700149, West Bengal, India.
Pallav SenguptaDepartment of Physiology, Vidyasagar College for Women, University of Calcutta, Kolkata, Pincode 700006, West Bengal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The quality of life for women after menopause is one of the key health issues today, and osteoporosis is a silently progressing metabolic bone disease widely prevalent in post-menopausal women in India. Rapid bone loss occurs in post-menopausal women due to hormonal factors that lead to an increased risk of fractures. Thus, the present study was undertaken to observe the serum calcium and alkaline phosphatase (ALP) levels in post-menopausal women as these substances are biochemical markers of bone metabolism. In this small-scale cross-sectional study, 100 samples were taken. Of these, 50 were taken from post-menopausal women (experimental group) and 50 were taken from pre-menopausal women (control group). Serum calcium and serum ALP were measured in the blood samples of both groups. The findings demonstrated that the serum calcium level was significantly lower in the post-menopausal group than in the pre-menopausal group, while the ALP level was slightly higher. Therefore, an increase in bone turnover accelerates bone mass reduction in post-menopausal women, whereas a decrease in bone turnover is associated with the preservation of bone mass.

Indexed as

alkaline phosphatasecalciummenopauseosteoporosis

Identifiers

PMID24639613
PMCPMC3952340

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.