ArticleProceedings of the National Academy of Sciences of the United States of America2014
Periodic root branching in Arabidopsis requires synthesis of an uncharacterized carotenoid derivative.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
53 citing papers in PubMed, 124 citations in OpenAlex.
- TOP1α-mediated stabilization of CYP82C4 G-quadruplex DNA represses lateral root primordium initiation in Arabidopsis.Nature plants · 2026Article
- Article
- Apocarotenoid signaling regulates meristem activity and shapes shoot and root lateral organ formation in Arabidopsis.Plant physiology · 2025Article
- Gibberellin dynamics governing nodulation revealed using GIBBERELLIN PERCEPTION SENSOR 2 in Medicago truncatula lateral organs.The Plant cell · 2024Article
- Shaping root architecture: towards understanding the mechanisms involved in lateral root development.Biology direct · 2024Review
- Exogenous application of the apocarotenoid retinaldehyde negatively regulates auxin-mediated root growth.Plant physiology · 2024Article
- Jasmonic Acid and Salicylic Acid improved resistance against Spodoptera frugiperda Infestation in maize by modulating growth and regulating redox homeostasis.Scientific reports · 2024Article
- Natural overexpression of CAROTENOID CLEAVAGE DIOXYGENASE 4 in tomato alters carotenoid flux.Plant physiology · 2023Article
- Cellular and gene expression patterns associated with root bifurcation in Selaginella.Plant physiology · 2022Article
- Overexpression of Sweet Potato Carotenoid Cleavage Dioxygenase 4 (International journal of molecular sciences · 2022Article
- The hidden half comes into the spotlight: Peeking inside the black box of root developmental phases.Plant communications · 2022Review
- Carotenoid-derived bioactive metabolites shape plant root architecture to adapt to the rhizospheric environments.Frontiers in plant science · 2022Review
- The Root Clock as a Signal Integrator System: Ensuring Balance for Survival.Frontiers in plant science · 2022Review
- A plant lipocalin promotes retinal-mediated oscillatory lateral root initiation.Science (New York, N.Y.) · 2021Article
- GUN control in retrograde signaling: How GENOMES UNCOUPLED proteins adjust nuclear gene expression to plastid biogenesis.The Plant cell · 2021Review
- Characterization of CYCLOPHILLIN38 shows that a photosynthesis-derived systemic signal controls lateral root emergence.Plant physiology · 2021Article
- Transformation of Long-Lived AlbinoFrontiers in plant science · 2021Article
- Recent progress in the chemistry and biochemistry of strigolactones.Journal of pesticide science · 2020Article
- AeLife · 2020Article
- The Apocarotenoid Zaxinone Is a Positive Regulator of Strigolactone and Abscisic Acid Biosynthesis in Arabidopsis Roots.Frontiers in plant science · 2020Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
In plants, continuous formation of lateral roots (LRs) facilitates efficient exploration of the soil environment. Roots can maximize developmental capacity in variable environmental conditions through establishment of sites competent to form LRs. This LR prepattern is established by a periodic oscillation in gene expression near the root tip. The spatial distribution of competent (prebranch) sites results from the interplay between this periodic process and primary root growth; yet, much about this oscillatory process and the formation of prebranch sites remains unknown. We find that disruption of carotenoid biosynthesis results in seedlings with very few LRs. Carotenoids are further required for the output of the LR clock because inhibition of carotenoid synthesis also results in fewer sites competent to form LRs. Genetic analyses and a carotenoid cleavage inhibitor indicate that an apocarotenoid, distinct from abscisic acid or strigolactone, is specifically required for LR formation. Expression of a key carotenoid biosynthesis gene occurs in a spatially specific pattern along the root's axis, suggesting spatial regulation of carotenoid synthesis. These results indicate that developmental prepatterning of LRs requires an uncharacterized carotenoid-derived molecule. We propose that this molecule functions non-cell-autonomously in establishment of the LR prepattern.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.