ArticleProceedings of the National Academy of Sciences of the United States of America2014
Embryonic thermosensitive TRPA1 determines transgenerational diapause phenotype of the silkworm, Bombyx mori.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 114 citations in OpenAlex.
- Polymorphism in Ontogenetic Duration inInsects · 2026Review
- The sensory ecology of caterpillars.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Review
- TRPA1 for Butterfly Eyespot Formation.International journal of molecular sciences · 2026Article
- Cryptochrome-mediated integration of circadian rhythms into seasonal cycles in the silkwormFrontiers in physiology · 2026Review
- Hot breath, quick exit: aphids flee mammalian heat via TRPA1.Science China. Life sciences · 2025Article
- Cold-Sensing TRP Channels and Temperature Preference Modulate Ovarian Development in the Model OrganismInternational journal of molecular sciences · 2025Article
- Heat activation desensitizes Aedes aegypti transient receptor potential ankyrin 1 (AaTRPA1) to chemical agonists that repel mosquitoes.Pesticide biochemistry and physiology · 2025Article
- Extreme genetic signatures of local adaptation in a notorious rice pest,National science review · 2025Article
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- Upf2-Mediated Nonsense-Mediated Degradation Pathway Involved in Genetic Compensation ofInsects · 2024Article
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- miR-252 targeting temperature receptoreLife · 2023Article
- The molecular mechanisms of diapause and diapause-like reversible arrest.Biochemical Society transactions · 2023Review
- A mother to offspring metabolic link.Nature cell biology · 2023Article
- Article
- Article
- Function of Transient Receptor Potential-Like Channel in Insect Egg Laying.Frontiers in molecular neuroscience · 2022Article
- Circadian and Neuroendocrine Basis of Photoperiodism Controlling Diapause in Insects and Mites: A Review.Frontiers in physiology · 2022Review
- Circadian Clock Genes Regulate Temperature-Dependent Diapause Induction in SilkwormFrontiers in physiology · 2022Article
- Circadian Clock GeneBiology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the bivoltine strain of the silkworm, Bombyx mori, embryonic diapause is induced transgenerationally as a maternal effect. Progeny diapause is determined by the environmental temperature during embryonic development of the mother; however, its molecular mechanisms are largely unknown. Here, we show that the Bombyx TRPA1 ortholog (BmTrpA1) acts as a thermosensitive transient receptor potential (TRP) channel that is activated at temperatures above ∼ 21 °C and affects the induction of diapause in progeny. In addition, we show that embryonic RNAi of BmTrpA1 affects diapause hormone release during pupal-adult development. This study identifying a thermosensitive TRP channel that acts as a molecular switch for a relatively long-term predictive adaptive response by inducing an alternative phenotype to seasonal polyphenism is unique.
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