Observational studyInternational journal of epidemiology2015
Cohort profile: project viva.
Abstract readObservational Study
In one paragraph
Observational study in International journal of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 307 papers, 7 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
307citing papers in PubMed, 7 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
307 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Cesarean delivery and blood DNA methylation at birth and childhood: Meta-analysis in the Pregnancy and Childhood Epigenetics Consortium.Science advances · 2024Pooled it
- Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills.Molecular psychiatry · 2022Pooled it
- DNA methylation changes associated with prenatal mercury exposure: A meta-analysis of prospective cohort studies from PACE consortium.Environmental research · 2022Pooled it
- Exposure to violence, chronic stress, nasal DNA methylation, and atopic asthma in children.Pediatric pulmonology · 2021Pooled it
- Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation.Molecular psychiatry · 2021Pooled it
- Comparison of Acetaminophen (Paracetamol) With Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years: A Systematic Review and Meta-analysis.JAMA network open · 2020Pooled it
- Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.Genome medicine · 2020Pooled it
- Association of cow's milk intake in early childhood with adiposity and cardiometabolic risk in early adolescence.The American journal of clinical nutrition · 2022Trial
- Maternal Prenatal Diet and Colic and Eczema Among Infants.JAMA network open · 2026Article
- Differences in socio-demographic and environmental exposures at home vs. school in the ECHO cohort.Journal of exposure science & environmental epidemiology · 2026Article
- Genetic Determinants of Macronutrient Intake Are Associated With Specific Food Intake in Youth: A Cohort Study Across Childhood and Adolescence.Diabetes care · 2026Article
- Prenatal adipose tissue estimation using early second trimester anthropometry.European journal of clinical nutrition · 2026Article
- Associations of prenatal metal exposures with autism-related outcomes in the ECHO cohort.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Associations of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) and childhood vaccine-induced immunity.Environmental health : a global access science source · 2026Article
- Joint Associations of Prenatal Per- and Polyfluoroalkyl Substances and Metal Mixtures with Adiposity in Childhood and Adolescence.Environmental science & technology · 2026Article
- Birth Weight Percentiles and Infant and Child Growth Dynamics.JAMA network open · 2026Article
- Associations of Colic and Excessive Crying in Infancy with Food Allergy Outcomes in Childhood and Adolescence.The Journal of pediatrics · 2026Article
- A two-step Bayesian clustering approach to relate PFAS mixture profiles and dietary patterns in early pregnancy.Environmental research · 2026Article
- A Large, Diverse, Urban Cardiovascular Health e-Cohort in Childhood and Adolescence: Protocol for the Young Hearts Study.JMIR research protocols · 2026Article
- Multi-Ancestry Epigenome-Wide Meta-Analysis Identifies Novel Bulk and Cell-Type-Specific Epigenetic Markers of Asthma with Severe Exacerbations.medRxiv : the preprint server for health sciences · 2026Article
247 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Emily OkenObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA emily_oken@hphc.org.
Andrea A BaccarelliObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, B
Diane R GoldObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, B
Ken P KleinmanObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Augusto A LitonjuaObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Dawn De MeoObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Janet W Rich-EdwardsObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, B
Sheryl L Rifas-ShimanObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Sharon SagivObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Elsie M TaverasObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, B
Scott T WeissObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Mandy B BelfortObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Heather H BurrisObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Carlos A CamargoObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Susanna Y HuhObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Christos MantzorosObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Margaret G ParkerObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA.
Matthew W GillmanObesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, USA, Department of Neonatology, Beth Israel Deaconess Medical Center, Boston, MA, USA, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA, Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA, Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, MA, USA and Division of Neonatology, Boston Medical Center and Boston University School of Medicine, Boston, MA, USA Obesity Prevention Program, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA, Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA, Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA, Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA, Connors Center for Women's Health and Gender Biology, Brigham and Women's Hospital, Boston, MA, USA, Department of Environmental Health, Boston University School of Public Health, Boston, MA, USA, Department of Nutrition, Harvard School of Public Health, Boston, MA, USA, Department of Pediatrics, Massachusetts General Hospital, Boston, MA, USA, Division of Newborn Medicine, B
Funding
Translational Research Support CoreP30ES000002 · NIEHS · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Brent Andrew Coull · 1985 to 2026
$44.6MPrenatal environmental determinants of health in young adulthood: a lifecourse approachR01HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Marie-France Hivert, Emily Oken · 1998 to 2026
$20.6MSleep Duration, Childhood Energy Balance, and Insulin Resistance in AdolescenceU54CA155626 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI STAMPFER, MEIR · 2011 to 2015
$9.6MCAREER DEVELOPMENT IN DIABETES RESEARCH FOR PEDIATRIC ENDOCRINOLOGISTSK12DK094721 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI LAFFEL, LORI M, WHITE, MORRIS F. · 2011 to 2021
$6.3MPre- and Peri-natal Predictors of Childhood ObesityR37HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI GILLMAN, MATTHEW W · 2012 to 2015
$4.5MThe Fetal and Childhood Environment, Oxidative Balance, Inflammation and AsthmaR01AI102960 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI GOLD, DIANE R, OKEN, EMILY · 2013 to 2017
$4.0MEarly Life DNA Methylation and Childhood Allergic DiseaseR01HL111108 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMEO, DAWN L · 2013 to 2016
$3.0MMaternal fatty acids, child obesity, and asthma immunityR01HL075504 · NHLBI · HARVARD PILGRIM HEALTH CARE, INC. · PI GILLMAN, MATTHEW W · 2004 to 2007
$2.4MRacial/Ethnic Disparities in Early Life Risk Factors for Childhood ObesityR01MD003963 · NIMHD · MASSACHUSETTS GENERAL HOSPITAL · PI TAVERAS BENAVIDEZ, ELSIE MIREYA · 2009 to 2013
$2.1MNovel Epigenomic Biomarkers of Prenatal Risk Factors, and Childhood ObesityR01NR013945 · NINR · HARVARD SCHOOL OF PUBLIC HEALTH · PI BACCARELLI, ANDREA · 2013 to 2015
$1.6MPatient-oriented research in early life origins of CVDK24HL068041 · NHLBI · HARVARD PILGRIM HEALTH CARE, INC. · PI GILLMAN, MATTHEW W · 2001 to 2010
$1.4MEffects of prenatal diet and mercury exposure on child behavior and developmentR01ES016314 · NIEHS · HARVARD PILGRIM HEALTH CARE, INC. · PI OKEN, EMILY · 2008 to 2011
$1.4MNCI NIH HHS U54 CA155626NHLBI NIH HHS K24 HL 068041NHLBI NIH HHS R01 HL 075504NHLBI NIH HHS R01HL111108NHLBI NIH HHS R01 HL 64925NIAID NIH HHS R01 AI 102960NIAID NIH HHS R01 AI102960NICHD NIH HHS K23 HD 044807NICHD NIH HHS K24 HD069408NICHD NIH HHS R01 HD 034568NICHD NIH HHS R01 HD034568NICHD NIH HHS R01 HD 034568-0951NICHD NIH HHS R01 HD 064925NICHD NIH HHS R37 HD034568NICHD NIH HHS R37HD 034568NICHD NIH HHS RC1 HD 063590NIDCR NIH HHS R03 DE14004NIDDK NIH HHS K12DK094721NIDDK NIH HHS K23 DK083817NIDDK NIH HHS R21DK 073739NIDDK NIH HHS R21 DK 082661NIDDK NIH HHS T32 DK 081505NIEHS NIH HHS K23 ES022242NIEHS NIH HHS P30 ES000002NIEHS NIH HHS R01 ES 016314NIEHS NIH HHS R01 ES21447NIMHD NIH HHS R01 MD 003963NIMH NIH HHS R01 MH 068596NINR NIH HHS R01 NR013945
Abstract
We established Project Viva to examine prenatal diet and other factors in relation to maternal and child health. We recruited pregnant women at their initial prenatal visit in eastern Massachusetts between 1999 and 2002. Exclusion criteria included multiple gestation, inability to answer questions in English, gestational age ≥22 weeks at recruitment and plans to move away before delivery. We completed in-person visits with mothers during pregnancy in the late first (median 9.9 weeks of gestation) and second (median 27.9 weeks) trimesters. We saw mothers and children in the hospital during the delivery admission and during infancy (median age 6.3 months), early childhood (median 3.2 years) and mid-childhood (median 7.7 years). We collected information from mothers via interviews and questionnaires, performed anthropometric and neurodevelopmental assessments and collected biosamples. We have collected additional information from medical records and from mailed questionnaires sent annually to mothers between in-person visits and to children beginning at age 9 years. From 2341 eligible women, there were 2128 live births; 1279 mother-child pairs provided data at the mid-childhood visit. Primary study outcomes include pregnancy outcomes, maternal mental and cardiometabolic health and child neurodevelopment, asthma/atopy and obesity/cardiometabolic health. Investigators interested in learning more about how to obtain Project Viva data can contact Project_Viva@hphc.org.
Indexed as
Body Weights and MeasuresChild DevelopmentDietMental HealthMothersAdultAsthmaBlood PressureBreast FeedingCardiovascular DiseasesChildChild, PreschoolDiabetes MellitusFemaleHealth BehaviorHumanschildhoodcohortnutritionobesityPregnancy
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