Evidence map›Paper›PMID 24639303›Full record

ArticleThe American journal of tropical medicine and hygiene2014

Detection of Schistosoma mansoni antibodies in a low-endemicity area using indirect immunofluorescence and circumoval precipitin test.

Maria Cristina Carvalho do Espírito-Santo, Pedro Luiz Pinto, Cybele Gargioni, Monica Viviana Alvarado-Mora, Vera Lúcia Pagliusi Castilho, João Ranato Rebello Pinho, Expedito José de Albuquerque Luna, Ronaldo Cesar Borges Gryschek

Erratum issuedOpen access · bronzeAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Advances in the Diagnosis of Human Schistosomiasis.Clinical microbiology reviews · 2015
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Maria Cristina Carvalho do Espírito-SantoDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Department of Enteroparasites at the Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Faculdade de Medicina da Universiddae de São Paulo, Brazil; Laboratory of Clinical Parasitology of the Central Laboratory, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, Brazil cristinasanto@usp.br.
Pedro Luiz PintoDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Department of Enteroparasites at the Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Faculdade de Medicina da Universiddae de São Paulo, Brazil; Laboratory of Clinical Parasitology of the Central Laboratory, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, Brazil.
Cybele GargioniDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Department of Enteroparasites at the Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Faculdade de Medicina da Universiddae de São Paulo, Brazil; Laboratory of Clinical Parasitology of the Central Laboratory, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, Brazil.
Monica Viviana Alvarado-MoraDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Department of Enteroparasites at the Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Faculdade de Medicina da Universiddae de São Paulo, Brazil; Laboratory of Clinical Parasitology of the Central Laboratory, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, Brazil.
Vera Lúcia Pagliusi CastilhoDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Department of Enteroparasites at the Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Faculdade de Medicina da Universiddae de São Paulo, Brazil; Laboratory of Clinical Parasitology of the Central Laboratory, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, Brazil.
João Ranato Rebello PinhoDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Department of Enteroparasites at the Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Faculdade de Medicina da Universiddae de São Paulo, Brazil; Laboratory of Clinical Parasitology of the Central Laboratory, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, Brazil.
Expedito José de Albuquerque LunaDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Department of Enteroparasites at the Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Faculdade de Medicina da Universiddae de São Paulo, Brazil; Laboratory of Clinical Parasitology of the Central Laboratory, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, Brazil.
Ronaldo Cesar Borges GryschekDepartment of Infectious and Parasitic Diseases, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Department of Enteroparasites at the Parasitology and Mycology, Instituto Adolfo Lutz, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Faculdade de Medicina da Universiddae de São Paulo, Brazil; Laboratory of Clinical Parasitology of the Central Laboratory, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Laboratory of Tropical Gastroenterology and Hepatology, Department of Gastroenterology, Instituto de Medicina Tropical de São Paulo, Universidade de São Paulo, São Paulo, Brazil.
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parasitological diagnostic methods for schistosomiasis lack sensitivity, especially in regions of low endemicity. The objective of this study was to determine the prevalence of Schistosoma mansoni infections by antibody detection using the indirect immunofluorescence assay (IFA-IgM) and circumoval precipitin test (COPT). Serum samples of 572 individuals were randomly selected. The IFA-IgM and COPT were used to detect anti-S. mansoni antibodies. Of the patients studied, 15.9% (N = 91) were IFA-IgM positive and 5.1% (N = 29) had COPT reactions (P < 0.001 by McNemar's test). Immunodiagnostic techniques showed higher infection prevalence than had been previously estimated. This study suggests that combined use of these diagnostic tools could be useful for the diagnosis of schistosomiasis in epidemiological studies in areas of low endemicity.

Indexed as

AdolescentAdultAgedAged, 80 and overAnimalsAntibodies, HelminthBrazilChildChild, PreschoolCross-Sectional StudiesFecesFemaleFluorescent Antibody Technique, IndirectHumansImmunoglobulin MInfantAntibodies, HelminthImmunoglobulin M

Identifiers

PMID24639303
PMCPMC4047744
OpenAlexW2090158541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.