ReviewPlant molecular biology2014
CRISPR-Cas system: a powerful tool for genome engineering.
Review in Plant molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Enhancing secondary metabolite accumulation in medicinal plants to improve immunomodulatory activity.Frontiers in pharmacology · 2026Review
- Review
- Evaluate the guide RNA effectivenessFrontiers in plant science · 2023Article
- Use of CRISPR-Cas tools to engineer Trichoderma species.Microbial biotechnology · 2022Review
- CRISPR-Cas gene editing technology and its application prospect in medicinal plants.Chinese medicine · 2022Review
- Recent Progresses in Electrochemical DNA Biosensors for SARS-CoV-2 Detection.Frontiers in bioengineering and biotechnology · 2022Review
- Combined fluorescent seed selection and multiplex CRISPR/Cas9 assembly for fast generation of multiple Arabidopsis mutants.Plant methods · 2021Article
- YSL3-mediated copper distribution is required for fertility, seed size and protein accumulation in Brachypodium.Plant physiology · 2021Article
- Genomic-Assisted Marker Development Suitable forFrontiers in plant science · 2021Article
- Validation of barley 2OGO gene as a functional orthologue of Arabidopsis DMR6 gene in Fusarium head blight susceptibility.Scientific reports · 2020Article
- Knock-out of TERMINAL FLOWER 1 genes altered flowering time and plant architecture in Brassica napus.BMC genetics · 2020Article
- Knockout ofFrontiers in oncology · 2020Article
- CRISPR/Cas9-mediated genome editing efficiently creates specific mutations at multiple loci using one sgRNA in Brassica napus.Scientific reports · 2017Article
- Heterologous expression of the yeast Tpo1p or Pdr5p membrane transporters in Arabidopsis confers plant xenobiotic tolerance.Scientific reports · 2017Article
- Development of broad virus resistance in non-transgenic cucumber using CRISPR/Cas9 technology.Molecular plant pathology · 2016Article
- The CRISPR/Cas Genome-Editing Tool: Application in Improvement of Crops.Frontiers in plant science · 2016Review
- [Application Progress of CRISPR/Cas9 System for Gene Editing in Tumor Research].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2015Review
- Coupling the CRISPR/Cas9 System with Lambda Red Recombineering Enables Simplified Chromosomal Gene Replacement in Escherichia coli.Applied and environmental microbiology · 2015Article
- Understanding the DNA damage response in order to achieve desired gene editing outcomes in mosquitoes.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2015Review
- Efficient gene editing in tomato in the first generation using the clustered regularly interspaced short palindromic repeats/CRISPR-associated9 system.Plant physiology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Targeted gene regulation on a genome-wide scale is a powerful strategy for interrogating, perturbing, and engineering cellular systems. Recent advances with the RNA-mediated Cas9 endonuclease derived from clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated proteins (Cas) systems have dramatically transformed our ability to specifically modify intact genomes of diverse cells and organisms. The CRISPR-Cas system has been adapted as an efficient, facile, and robust gene-targeting technology with the potential for high-throughput and multiplexed genome engineering. Exciting breakthroughs in understanding the mechanisms of the CRISPR-Cas system and its enormous potential for applications across basic science, agricultural and biotechnology.
Indexed as
Identifiers
24639266What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.