ReviewSeminars in immunopathology2014
Ectoenzymes in leukocyte migration and their therapeutic potential.
Review in Seminars in immunopathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review: Targeted Molecular Imaging of Angiogenesis and Its Mediators in Rheumatoid Arthritis.International journal of molecular sciences · 2022Pooled it
- Vascular-adhesion protein 1 in giant cell arteritis and polymyalgia rheumatica.Frontiers in medicine · 2024Review
- Leukocyte Membrane Enzymes Play the Cell Adhesion Game.Frontiers in immunology · 2021Review
- Human Copper-Containing Amine Oxidases in Drug Design and Development.Molecules (Basel, Switzerland) · 2020Review
- Vascular Adhesion Protein-1 (VAP-1) as Predictor of Radiographic Severity in Symptomatic Knee Osteoarthritis in the New York University Cohort.International journal of molecular sciences · 2019Article
- Vascular Adhesion Protein-1: A Cell Surface Amine Oxidase in Translation.Antioxidants & redox signaling · 2019Review
- Ectonucleotidases in Blood Malignancies: A Tale of Surface Markers and Therapeutic Targets.Frontiers in immunology · 2019Review
- Article
- Mapping the interaction site and effect of the Siglec-9 inflammatory biomarker on human primary amine oxidase.Scientific reports · 2018Article
- Comparison ofContrast media & molecular imaging · 2017Article
- Developing Treatments for Chronic Kidney Disease in the 21st Century.Seminars in nephrology · 2016Review
- Article
- 68Ga-DOTA-Siglec-9--a new imaging tool to detect synovitis.Arthritis research & therapy · 2015Article
- How leukocytes cross the vascular endothelium.Nature reviews. Immunology · 2015Review
- Primary Amine Oxidase of Escherichia coli Is a Metabolic Enzyme that Can Use a Human Leukocyte Molecule as a Substrate.PloS one · 2015Article
- Introduction for the special issue on new paradigms in leukocyte trafficking, lessons for therapeutics.Seminars in immunopathology · 2014Article
- Consequences of the lack of CD73 and prostatic acid phosphatase in the lymphoid organs.Mediators of inflammation · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammation causes or accompanies a huge variety of diseases. Migration of leukocytes from the blood into the tissues, in the tissues, and from the tissues to lymphatic vasculature is crucial in the formation and resolution of inflammatory infiltrates. In addition to classical adhesion and activation molecules, several other molecules are known to contribute to the leukocyte traffic. Several of them belong to ectoenzymes, which are cell surface molecules having catalytically active sites outside the cell. We will review here how several ectoenzymes present on leukocytes or endothelial cell surface function as adhesins and/or modulate the extravasation cascade through their enzymatic activities. Moreover, their therapeutic potential as immune modulators in different experimental inflammation models and in clinical trials will be discussed.
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