ArticleInternational orthopaedics2014
Prosthetic joint infection following total hip replacement: results of one-stage versus two-stage exchange.
Article in International orthopaedics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
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Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Comparative reinfection rate of one-stage versus two-stage revision in the management of periprosthetic joint infection following total hip arthroplasty: a meta-analysis.BMC musculoskeletal disorders · 2024Pooled it
- Systematic review and meta-analysis of single-stage vs two-stage revision for periprosthetic joint infection: a call for a prospective randomized trial.BMC musculoskeletal disorders · 2024Pooled it
- Does cemented or cementless single-stage exchange arthroplasty of chronic periprosthetic hip infections provide similar infection rates to a two-stage? A systematic review.BMC infectious diseases · 2016Pooled it
- Short-term outcomes of articular cement spacer in the treatment of prosthetic knee joint infections: a retrospective case series.Singapore medical journal · 2026Article
- Biomechanical Properties of Bone Cement Impregnated with Vancomycin and Ceftazidime: An In Vitro Experimental Lab Study.Indian journal of orthopaedics · 2026Article
- Infection management in hip arthroplasty: Comparative insights on revision strategies.Journal of clinical orthopaedics and trauma · 2025Article
- Single-Stage Revision for Treatment of Prosthetic Joint Infection in Total Hip Arthroplasty.Indian journal of orthopaedics · 2025Review
- Article
- Surgical treatment of periprosthetic joint infection: Two stage or one stage?Joint diseases and related surgery · 2025Article
- What Is the Role of Local Antimicrobial Protection for One-Stage Revision for Peri-Prosthetic Hip Infection?Antibiotics (Basel, Switzerland) · 2024Review
- Utilizing an antibiotic-eluting articulated cemented spacer in the two-stage management of infected total hip arthroplasty: a technical note.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Appropriate Duration of Antimicrobial Treatment for Prosthetic Joint Infections: A Narrative Review.Antibiotics (Basel, Switzerland) · 2024Review
- Comparison of Surgical Procedures in the Treatment of Hip Periprosthetic Infection.Revista brasileira de ortopedia · 2023Article
- Making the diagnosis in prosthetic joint infection: a European view.EFORT open reviews · 2023Review
- Repeat two-stage exchange arthroplasty for recurrent periprosthetic hip or knee infection: what are the chances for success?Archives of orthopaedic and trauma surgery · 2023Article
- Comparison of Static and Articulating Spacers After Periprosthetic Joint Infection.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2023Article
- Early periprosthetic hip joint infection managed by cementless one-stage revision - a case series.Journal of bone and joint infection · 2022Article
- Long-Term Outcomes of Staged Revision Surgery for Chronic Periprosthetic Joint Infection of Total Hip Arthroplasty.Journal of clinical medicine · 2021Article
- What is the appropriate extended duration of antibiotic prophylaxis after two-stage revision for chronic PJI?Bone & joint research · 2021Article
- No differences in short-term outcomes between patients with anaerobic and aerobic culture positive prosthetic joint infection.Journal of clinical orthopaedics and trauma · 2021Article
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeProsthetic hip joint infection remains a challenging socio-economic problem. Curative treatment is usually a one- or two-stage revision surgery, but neither of these options has yet emerged as the treatment of choice. The aim of this study was to evaluate which of these methods produced superior outcomes.
methodsA retrospective study was performed including 92 patients with deep infections after implantation of primary total hip arthroplasty (THA) who had undergone either one-stage or two-stage revision surgery at a single centre. Infections were classified according to McPherson and we evaluated the rate of persisting infection or reinfection after surgical intervention.
resultsThe two-stage revision surgery revealed superior outcomes for the analysed infection categories compared to the one-stage procedure except for the least serious category of infections (i.e. McPherson Stage I/A/1, early postoperative infection, no systemic comorbidities, local status uncompromised). Eradication of prosthetic infection was achieved in 94.5 % (n = 52) within the group of two-stage exchange, and 56.8 % (n = 21) of patients treated with a one-stage procedure. Outcome of patients following a one-stage or a two-stage exchange was overall significantly different with p < 0.001. Further deviations between the described two procedures were noted in the subgroups following the classification described by McPherson.
conclusionsOur results indicate superiority of two-stage revision surgery in case of serious infections. The authors believe that decisions on the surgical approach for the treatment of deep prosthesis infections should be made on the basis of standardized staging systems.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.