Evidence map›Paper›PMID 24638214›Full record

ArticleInternational orthopaedics2014

Repeated metal ion measurements in patients with high risk metal-on-metal hip replacement.

Aleksi Reito, Teemu Moilanen, Timo Puolakka, Jorma Pajamäki, Antti Eskelinen

Open access · bronzeAbstract read
In one paragraph

Article in International orthopaedics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Midterm results of the Birmingham hip resurfacing: a single-surgeon series.Archives of orthopaedic and trauma surgery · 2023
    Article
  3. How much does a Medical and Healthcare Products Regulatory Agency medical device alert for metal-on-metal hip arthroplasty patients really cost?Hip international : the journal of clinical and experimental research on hip pathology and therapy · 2022
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aleksi ReitoCoxa Hospital for Joint Replacement, P.O. Box 652, 33101, Tampere, Finland, aleksi.reito@uta.fi.
Teemu Moilanen
Timo Puolakka
Jorma Pajamäki
Antti Eskelinen
Coxa Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeConventional follow-up methods are not sufficient to identify adverse soft tissue reactions in patients with metal-on-metal hip replacements. The national guidelines regarding metal ion measurements are debatable. The aims of our study were to investigate (1) if there is a clinically significant change in whole blood (WB) cobalt (Co) or chrome (Cr) levels in repeated WB assessment in patients operated on with ASR hip replacements, and (2) what proportion of patients has WB Co or Cr level below the previously established safe upper limits (SUL) in the repeated WB metal ion assessment.

methodsWe identified all patients (n = 254) with unilateral ASR implants who had second blood sample taken eight to 16 months after the first.

resultsWB Co and Cr levels remained below SUL and within their initial values during a mean one-year measurement interval in the majority of patients with a high risk HR device. In contrast to this, 50 % of patients with THRs had metal ion levels exceeding the SUL in the first measurement. WB Co values significantly increased over the measurement interval in the THR group.

conclusionIn patients with a high risk HR, repeated metal ion measurement did not provide useful information for clinical decision-making. In patients with a LD MoM THR repeated measurements revealed a large number of patients with metal ion levels exceeding SUL and might thus be clinically beneficial.

Indexed as

Prosthesis FailureAgedArthroplasty, Replacement, HipChromiumCobaltFemaleHip JointHip ProsthesisHumansIonsMaleMetals, HeavyMiddle AgedOsteoarthritis, HipProsthesis DesignChromiumCobaltIonsMetals, Heavy

Identifiers

PMID24638214
PMCPMC4071495
OpenAlexW2007601884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.