Evidence map›Paper›PMID 24637898›Full record

ArticleBone marrow transplantation2014

Hematopoietic SCT in Europe: data and trends in 2012 with special consideration of pediatric transplantation.

J R Passweg, H Baldomero, C Peters, H B Gaspar, S Cesaro, P Dreger, R F Duarte, J H F Falkenburg, D Farge-Bancel, A Gennery and 9 more

Abstract read
In one paragraph

Article in Bone marrow transplantation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Neurologic complications after allogeneic transplantation: a meta-analysis.Annals of clinical and translational neurology · 2019
    Pooled it
  2. Trial
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  14. Impact of Clinical Parameters and Induction Regimens on Peripheral Blood Stem-Cell Mobilization and Collection in Multiple Myeloma Patients.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2023
    Article
  15. The Impact of Cellular Therapies on Gastrointestinal Diseases: Applications and Challenges.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023
    Review
  16. Article
  17. Article
  18. Article
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  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

J R PasswegEBMT Activity Survey Office, Division of Hematology, Department of Medicine, University Hospital, Basel, Switzerland.
H BaldomeroEBMT Activity Survey Office, Division of Hematology, Department of Medicine, University Hospital, Basel, Switzerland.
C PetersBMT Unit, St Anna Kinderspital, Vienna, Austria.ORCID 0000000303698515
H B GasparMolecular Immunology Unit, UCL Institute of Child Health, London, UK.
S CesaroPaediatric HaematologyOncology, Policlinico G.B. Rossi, Verona, Italy.
P DregerUniversity of Heidelberg, Medizinische Klinik u. Poliklinik V, Heidelberg, Germany.
R F DuarteInstitut Catalàd'Oncologia, Hospital Duran i Reynals, Barcelona, Spain.
J H F FalkenburgDepartment of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
D Farge-BancelService de Médecine Interne, Hopital St Louis, Paris, France.
A GenneryChildren's BMT Unit, Great North Children's Hospital, Royal Victoria Infirmary, Newcastle-Upon-Tyne, UK.
J HalterJACIE Accreditation Committee, Basel, Switzerland.
N KrögerUniversity Hospital Eppendorf, Hamburg, Germany.
F LanzaSt Anna Hospital, Ferrare, Italy.
J MarshDepartment of Haematological Medicine, GKT School of Medicine, London, UK.
M MohtyINSERM UMRs 938, Universite Pierre & Maris Curie, Hôpital Saint Antoine, Paris, France.
A SuredaDepartment of Haematology, Addenbrookes Hospital, Cambridge, UK.
A VelardiOspedale Santa Maria della Misericordia - Sezione di Ematologia, LocalitáSant Andrea delle Fratte, Perugia, Italy.
A MadrigalAnthony Nolan Research Institute, Royal Free Hospital, London, UK.
European Society for Blood and Marrow Transplantation EBMT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In all, 661 of 680 centers in 48 countries reported 37 818 hematopoietic SCT (HSCT) in 33 678 patients (14 165 allogeneic (42%), 19 513 autologous (58%)) in the 2012 survey. Main indications were leukemias, 10 641 (32%; 95% allogeneic); lymphoid neoplasias, 19 336 (57%; 11% allogeneic); solid tumors, 1630 (5%; 3% allogeneic); and nonmalignant disorders, 1953 (6%; 90% allogeneic). There were more unrelated donors than HLA-identical sibling donors (54% versus 38% (8% being mismatched related donor HSCT)). Cord blood was almost exclusive in allogeneic transplants (5% of total). Since 2011, the highest increases in allogeneic HSCT were for AML in CR1 (12%) and for myeloproliferative neoplasm (15%). For autologous HSCT the main increases were for plasma cell disorders (7%), non-Hodgkin lymphoma (4%) and autoimmune disease (50%). There were 4097 pediatric patients <18 years of age receiving HSCT, 2902 received an allogeneic and 1195 an autologous HSCT. Overall, 69% of allogeneic and 64% of autologous HSCT were performed in dedicated pediatric centers and the remainder in combined adult and pediatric centers. Distributions of diseases, donor types and stem cell source for all patients and pediatric patients in particular are shown. A percentage of centers fulfilling the annual required criteria for patient numbers for JACIE accreditation are provided.

Indexed as

AdultAllograftsAutograftsBone Marrow TransplantationChildCord Blood Stem Cell TransplantationData CollectionEuropeHematopoietic Stem Cell TransplantationHumansTissue Donors

Identifiers

PMID24637898
PMCPMC4051369

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.