Evidence map›Paper›PMID 24637892›Full record

ArticlePloS one2014

Diurnal intermittent fasting during Ramadan: the effects on leptin and ghrelin levels.

Mohammed A Alzoghaibi, Seithikurippu R Pandi-Perumal, Munir M Sharif, Ahmed S BaHammam

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Effects of Ramadan Intermittent Fasting on Gut Hormones and Body Composition in Males with Obesity.International journal of environmental research and public health · 2020
    Trial
  6. Article
  7. Review
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  10. Article
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  13. Article
  14. As a phenomenon: Ramadan fasting improves olfactory performance.Laryngoscope investigative otolaryngology · 2024
    Article
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  19. Review
  20. Moderation of mitochondrial respiration mitigates metabolic syndrome of aging.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mohammed A AlzoghaibiDepartment of Physiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; National Plan for Science and Technology, King Saud University, Riyadh, Saudi Arabia.
Seithikurippu R Pandi-PerumalCenter for Healthful Behavior Change, Division of Health and Behavior, Department of Population Health, New York University Langone Medical Center, Clinical and Translational Research Institute, New York, New York, United States of America; Somnogen Canada Inc., Toronto, Ontario, Canada.
Munir M SharifThe University Sleep Disorders Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia; National Plan for Science and Technology, King Saud University, Riyadh, Saudi Arabia.
Ahmed S BaHammamThe University Sleep Disorders Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia; National Plan for Science and Technology, King Saud University, Riyadh, Saudi Arabia.
King Saud University · SANYU Langone Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to assess the effect of Islamic intermittent fasting, during and outside of Ramadan, on plasma levels of leptin and ghrelin while controlling for several potential confounding variables. Eight healthy male volunteers with a mean age of 26.6±4.9 years reported to the sleep disorders center (SDC) at King Saud University on four occasions: 1) adaptation; 2) 4 weeks before Ramadan while performing Islamic fasting for 1 week (baseline fasting) (BLF); 3) 1 week before Ramadan (non-fasting baseline) (BL); and 4) during the second week of Ramadan while fasting. Plasma leptin and ghrelin levels were measured using enzyme-linked immunoassays at 22:00, 02:00, 04:00, 06:00, and 11:00. During BLF, there were significant reductions in plasma leptin concentrations at 22:00 and 02:00 compared with the baseline concentrations (at 22:00: 194.2±177.2 vs. 146.7±174.5; at 02:00: 203.8±189.5 vs. 168.1±178.1; p<0.05). During Ramadan, there was a significant reduction in plasma leptin levels at 22:00 (194.2±177.2 vs. 132.6±130.4, p<0.05). No significant difference in plasma ghrelin concentrations was detected during the BL, BLF, or Ramadan periods. Cosinor analyses of leptin and ghrelin plasma levels revealed no significant changes in the acrophases of the hormones during the three periods. The nocturnal reduction in plasma leptin levels during fasting may be the result of the changes in meal times during fasting.

Indexed as

AdultCircadian RhythmEnergy MetabolismFastingGhrelinHumansIslamLeptinMaleSleepYoung AdultGhrelinLeptin

Identifiers

PMID24637892
PMCPMC3956913
OpenAlexW2081683648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.