Evidence map›Paper›PMID 24637839›Full record

ReviewNucleus (Austin, Tex.)

Nuclear function of Alus.

Chen Wang, Sui Huang

Open access · goldAbstract readReview
In one paragraph

Review in Nucleus (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. TDP-43 regulates transcription at protein-coding genes and Alu retrotransposons.Biochimica et biophysica acta. Gene regulatory mechanisms · 2019
    Article
  3. Article
  4. Potential application of cell reprogramming techniques for cancer research.Cellular and molecular life sciences : CMLS · 2019
    Review
  5. Association of Serotonin Transporter Gene AluJb Methylation with Major Depression, Amygdala Responsiveness, 5-HTTLPR/rs25531 Polymorphism, and Stress.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2018
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Regulation of human MAPT gene expression.Molecular neurodegeneration · 2015
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chen WangDepartment of Cell and Molecular Biology; Northwestern University; Feinberg School of Medicine; Chicago, IL USA.
Sui HuangDepartment of Cell and Molecular Biology; Northwestern University; Feinberg School of Medicine; Chicago, IL USA.
Northwestern University · US

Funding

The Structure and Function of Perinucleolar CompartmentR01GM078555 · NIGMS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HUANG, SUI · 2007 to 2015
$2.6M
NIGMS NIH HHS 2R01GM078555-05NIGMS NIH HHS R01 GM078555
6 · The paper itself

Abstract

Alus are transposable elements belonging to the short interspersed element family. They occupy over 10% of human genome and have been spreading through genomes over the past 65 million years. In the past, they were considered junk DNA with little function that took up genome volumes. Today, Alus and other transposable elements emerge to be key players in cellular function, including genomic activities, gene expression regulations, and evolution. Here we summarize the current understanding of Alu function in genome and gene expression regulation in human cell nuclei.

Indexed as

Alu ElementsCell NucleusDNA DamageDNA Transposable ElementsHumansTranscription, GeneticDNA Transposable Elementsalusevolutiongene expression regulationgenome functiontransposable elements

Identifiers

PMID24637839
PMCPMC4049919
OpenAlexW1991296387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.