Evidence map›Paper›PMID 24637634›Full record

ArticleScientific reports2014

Synthesis, cytotoxicity, and hydroxyapatite formation in 27-Tris-SBF for sol-gel based CaO-P2O5-SiO2-B2O3-ZnO bioactive glasses.

Gurbinder Kaur, G Pickrell, G Kimsawatde, D Homa, H A Allbee, N Sriranganathan

Abstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Silicon Nitride as a Biomedical Material: An Overview.International journal of molecular sciences · 2022
    Review
  8. Review
  9. A cost effective SiOProgress in biomaterials · 2020
    Article
  10. Article
  11. Article
  12. Antibacterial and anticancerous drug loading kinetics for (10-x)CuO-xZnO-20CaO-60SiOJournal of materials science. Materials in medicine · 2017
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gurbinder KaurDepartment of Material Science and Engineering, Holden Hall, Virginia Polytechnic Institute and State University, Blacksburg, Virginia-24060, USA.
G PickrellDepartment of Material Science and Engineering, Holden Hall, Virginia Polytechnic Institute and State University, Blacksburg, Virginia-24060, USA.
G KimsawatdeDepartment of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia-24060, USA.
D HomaDepartment of Material Science and Engineering, Holden Hall, Virginia Polytechnic Institute and State University, Blacksburg, Virginia-24060, USA.
H A AllbeeDepartment of Material Science and Engineering, Holden Hall, Virginia Polytechnic Institute and State University, Blacksburg, Virginia-24060, USA.
N SriranganathanDepartment of Biomedical Sciences and Pathobiology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia-24060, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CaO-P2O5-SiO2-B2O3-ZnO bioactive glasses were prepared via an optimized sol-gel method. The current investigation was focused on producing novel zinc based calcium phosphoborosilicate glasses and to evaluate their mechanical, rheological, and biocompatible properties. The morphology and composition of these glasses were studied using X-ray diffraction (XRD) and scanning electron microscopy (SEM). The particle size, mechanical and flexural strength was also determined. Furthermore, the zeta potential of all the glasses were determined to estimate their flocculation tendency. The thermal analysis and weight loss measurements were carried out using differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) respectively. For assessing the in-vitro bioactive character of synthesized glasses, the ability for apatite formation on their surface upon their immersion in simulated body fluid (SBF) was checked using SEM and pH measurements. MTS assay cytotoxicity assay and live-dead cell viability test were conducted on J774A.1 cells murine macrophage cells for different glass concentrations.

Indexed as

AnimalsBiomimetic MaterialsBody FluidsBoron CompoundsCalcium CompoundsCell LineCell SurvivalDurapatiteGlassMacrophagesMaterials TestingMiceOxidesPhase TransitionPhosphorus CompoundsSilicatesBoron CompoundsCalcium CompoundsDurapatitelimeOxidesPhosphorus CompoundsSilicatesSilicon DioxideZinc Oxide

Identifiers

PMID24637634
PMCPMC3957134

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.