Evidence map›Paper›PMID 24637394›Full record

ArticleNucleus (Austin, Tex.)

Repeated TALEs: visualizing DNA sequence localization and chromosome dynamics in live cells.

Thoru Pederson

Abstract readComment
In one paragraph

Article in Nucleus (Austin, Tex.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. CRISPR/Cas9 in Genome Editing and Beyond.Annual review of biochemistry · 2016
    Review
  3. Article
  4. Article
  5. Multicolor CRISPR labeling of chromosomal loci in human cells.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Thoru PedersonProgram in Cell and Developmental Dynamics; Department of Biochemistry and Molecular Pharmacology; University of Massachusetts Medical School; Worcester, MA USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three recent papers, published just weeks apart, describe the use of fluorescent TALEs to tag specific DNA sequences in live cells and, in one case, also in fixed cells, the latter with potential clinical applications.

Indexed as

DNA-Binding ProteinsAnimalsCell NucleusChromatinChromosomes, HumanDNA, SatelliteFluorescent DyesHumansMicroscopy, FluorescenceRepetitive Sequences, Nucleic AcidStaining and LabelingTranscriptional ActivationChromatinDNA-Binding ProteinsDNA, SatelliteFluorescent Dyescell cyclecentromeresDNA replication timingsingle nucleotide polymorphismstelomerestranscription activator-like effectors

Identifiers

PMID24637394
PMCPMC4028351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.