Evidence map›Paper›PMID 24636254›Full record

ArticleDevelopmental cell2014

Breaking up isn't easy: myosin V and its cargoes need Dma1 ubiquitin ligase's help.

Michael Winding, Vladimir I Gelfand

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Developmental cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michael WindingDepartment of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Vladimir I GelfandDepartment of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address: vgelfand@northwestern.edu.

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
REGULATION OF MYOSIN DRIVEN ORGANELLE TRANSPORTR01GM052111 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI GELFAND, VLADIMIR I · 1999 to 2018
$8.3M
NCI NIH HHS P30 CA060553NIGMS NIH HHS R01 GM052111
6 · The paper itself

Abstract

In this issue of Developmental Cell, Yau et al. (2014) report that degradation of cargo adapters releases yeast vacuoles and peroxisomes from myosin V (Myo2) and terminates organelle transport from the mother cell to the bud.

Indexed as

Cell Cycle ProteinsMyosin Heavy ChainsMyosin Type VOrganellesPeroxisomesReceptors, Cell SurfaceSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsVacuolesVesicular Transport ProteinsCell Cycle ProteinsDma1 protein, S cerevisiaeMYO2 protein, S cerevisiaeMyosin Heavy ChainsMyosin Type VReceptors, Cell SurfaceSaccharomyces cerevisiae ProteinsVAC17 protein, S cerevisiaeVesicular Transport Proteins

Identifiers

PMID24636254
PMCPMC4018999

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.