The ProCESS trial--a new era of sepsis management.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it.

1. Liberal Versus Restrictive Intravenous Fluid Therapy for Early Septic Shock: Rationale for a Randomized Trial.Annals of emergency medicine · 2018
   Pooled it
2. The Effect of Early Goal-Directed Therapy on Outcome in Adult Severe Sepsis and Septic Shock Patients: A Meta-Analysis of Randomized Clinical Trials.Anesthesia and analgesia · 2016
   Pooled it
3. Comparison of the effects of albumin and crystalloid on mortality in adult patients with severe sepsis and septic shock: a meta-analysis of randomized clinical trials.Critical care (London, England) · 2014
   Pooled it
4. The German Quality Network Sepsis: study protocol for the evaluation of a quality collaborative on decreasing sepsis-related mortality in a quasi-experimental difference-in-differences design.Implementation science : IS · 2018
   Trial
5. Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial.Intensive care medicine · 2017
   Trial
6. Lactate's impact on immune cells in sepsis: unraveling the complex interplay.Frontiers in immunology · 2024
   Review
7. Bacterial sepsis : Diagnostics and calculated antibiotic therapy.Der Anaesthesist · 2019
   Review
8. Sepsis: Early Recognition and Optimized Treatment.Tuberculosis and respiratory diseases · 2019
   Review
9. Endorsing performance measures is a matter of trust.BMJ (Clinical research ed.) · 2018
   Article
10. The impact of a multifaceted intervention including sepsis electronic alert system and sepsis response team on the outcomes of patients with sepsis and septic shock.Annals of intensive care · 2017
    Article
11. [Bacterial sepsis : Diagnostics and calculated antibiotic therapy].Der Anaesthesist · 2017
    Review
12. Searching for Staircases: Strengthening the Connections Between the Emergency Department and the Intensive Care Unit.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2017
    Article
13. Chloride alterations in hospitalized patients: Prevalence and outcome significance.PloS one · 2017
    Article
14. Inferior Vena Cava Collapsibility Index is a Valuable and Non-Invasive Index for Elevated General Heart End-Diastolic Volume Index Estimation in Septic Shock Patients.Medical science monitor : international medical journal of experimental and clinical research · 2016
    Article
15. Prospective evaluation of an automated method to identify patients with severe sepsis or septic shock in the emergency department.BMC emergency medicine · 2016
    Article
16. Temporal trends in the utilization of vasopressors in intensive care units: an epidemiologic study.BMC pharmacology & toxicology · 2016
    Article
17. Hospital Incidence and Mortality Rates of Sepsis.Deutsches Arzteblatt international · 2016
    Article
18. Prognostic utility of plasma lactate measured between 24 and 48 h after initiation of early goal-directed therapy in the management of sepsis, severe sepsis, and septic shock.Journal of intensive care · 2016
    Article
19. Comparison of Two Sepsis Recognition Methods in a Pediatric Emergency Department.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2015
    Observational
20. Early goal-directed therapy vs usual care in the treatment of severe sepsis and septic shock: a systematic review and meta-analysis.Internal and emergency medicine · 2015
    Article

Corrections and comments

• Commented on by
  Protocol-based care for early septic shock.2014
• Commented on by
  Protocol-based care for early septic shock.2014
• Comment on
  A randomized trial of protocol-based care for early septic shock.2014

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

Indexed as