Trial reportJournal of the American Geriatrics Society2014
Respiratory impairment and dyspnea and their associations with physical inactivity and mobility in sedentary community-dwelling older persons.
Trial report in Journal of the American Geriatrics Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04559659 (Study of the Relationship Between Respiratory Muscle Strenght, Peripheral Muscle Blood Flow and Gait Speed in the Elderly), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study of the Relationship Between Respiratory Muscle Strenght, Peripheral Muscle Blood Flow and Gait Speed in the Elderly
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Mitochondrial DNA variants and pulmonary function in older persons.Experimental gerontology · 2019Pooled it
- Trial
- Effect of Structured Physical Activity on Respiratory Outcomes in Sedentary Elderly Adults with Mobility Limitations.Journal of the American Geriatrics Society · 2016Trial
- Smoking quitting promotes neuromuscular and cartilage recovery in knee osteoarthritis.European journal of applied physiology · 2026Article
- Risk factors for community-acquired pneumonia in older adults in Japan after the introduction of the childhood PCV13.BMC infectious diseases · 2026Article
- Sarcopenia and sepsis fuel a self-perpetuating cycle of immunometabolism decline.Frontiers in immunology · 2026Review
- Effect of Menthol on Dyspnea During Exercise in Individuals With COPD.Archives of rehabilitation research and clinical translation · 2025Article
- Article
- Article
- Activity-Related Breathlessness and Physical Activity in Women with Sedentary Behavior: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2025Article
- Development of a Longitudinal Model for Disability Prediction in Older Adults in China: Analysis of CHARLS Data (2015-2020).JMIR aging · 2025Article
- Descriptive Study on the Relationship between Dyspnea, Physical Performance, and Functionality in Oncology Patients.Healthcare (Basel, Switzerland) · 2024Article
- Changes in pulmonary function following thoracic spine manipulation in a healthy inactive older adult population-a pilot study.Journal of physical therapy science · 2023Article
- Respiratory sarcopenia: A position paper by four professional organizations.Geriatrics & gerontology international · 2023Article
- Respiratory Sarcopenia and Sarcopenic Respiratory Disability: Concepts, Diagnosis, and Treatment.The journal of nutrition, health & aging · 2021Article
- Antihypertensive medications and physical function in older persons.Experimental gerontology · 2020Article
- Dyspnea is associated with poor physical performance among community-dwelling older adults: a population-based cross-sectional study.Sao Paulo medical journal = Revista paulista de medicina · 2020Article
- FEVRespiratory care · 2020Article
- Association of respiratory function with physical performance, physical activity, and sedentary behavior in older adults.Journal of physical therapy science · 2020Article
- Association of Breathing Reserve at Peak Exercise With Body Composition and Physical Function in Older Adults With Obesity.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 7 institutions in 1 country.
Funding
Abstract
objectivesTo evaluate the prevalence of respiratory impairment and dyspnea and their associations with objectively measured physical inactivity and performance-based mobility in sedentary older persons.
designCross-sectional.
settingLifestyle Interventions and Independence for Elders Study.
participantsCommunity-dwelling older persons (n = 1,635, mean age 78.9) who reported being sedentary (<20 min/wk of regular physical activity and <125 min/wk of moderate physical activity in past month). MEASUREMENTS: Respiratory impairment was defined as low ventilatory capacity (forced expiratory volume in 1 second less than lower limit of normal (LLN)) and respiratory muscle weakness (maximal inspiratory pressure <LLN). Dyspnea was defined as moderate to severe ratings on the modified Borg index, immediately after a 400-m walk test (400-MWT). Physical inactivity was defined according to high sedentary time as the highest quartile of participants with accelerometry-measured activity of <100 counts/min. Performance-based mobility was evaluated using the Short Physical Performance Battery (≤ 7 defined as moderate to severe mobility impairment) and 400-MWT gait speed (<0.8 m/s defined as slow).
resultsPrevalence rates were 17.7% for low ventilatory capacity, 14.7% for respiratory muscle weakness, 31.6% for dyspnea, 44.7% for moderate to severe mobility impairment and 43.6% for slow gait speed. Significant associations were found between low ventilatory capacity and slow gait speed (adjusted odds ratio (aOR) = 1.41, 95% confidence interval (CI) = 1.03-1.92), between respiratory muscle weakness and moderate to severe mobility impairment (aOR = 1.42, 95% CI = 1.03-1.95), and between dyspnea and high sedentary time (aOR = 1.98, 95% CI = 1.28-3.06) and slow gait speed (aOR = 1.70, 95% CI = 1.22-2.38).
conclusionRespiratory impairment and dyspnea are prevalent in sedentary older persons and are associated with objectively measured physical inactivity and poor performance-based mobility. Because they are modifiable, respiratory impairment and dyspnea should be considered in the evaluation of sedentary older persons.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.