ArticleThe Plant journal : for cell and molecular biology2014
Association of cytochrome b5 with ETR1 ethylene receptor signaling through RTE1 in Arabidopsis.
Article in The Plant journal : for cell and molecular biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 58 citations in OpenAlex.
- Ethylene, a Signaling Compound Involved in Seed Germination and Dormancy.Plants (Basel, Switzerland) · 2024Review
- Interactome of Arabidopsis Thaliana.Plants (Basel, Switzerland) · 2022Article
- CytochromeFrontiers in plant science · 2022Review
- An endoplasmic reticulum-localized cytochromeProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Comparative transcriptome analysis reveals new molecular pathways for cucumber genes related to sex determination.Plant reproduction · 2019Article
- Article
- Arabidopsis CPR5 regulates ethylene signaling via molecular association with the ETR1 receptor.Journal of integrative plant biology · 2017Article
- Molecular association of Arabidopsis RTH with its homolog RTE1 in regulating ethylene signaling.Journal of experimental botany · 2017Article
- Proteomes and Ubiquitylomes Analysis Reveals the Involvement of Ubiquitination in Protein Degradation in Petunias.Plant physiology · 2017Article
- Assembly of Dynamic P450-Mediated Metabolons-Order Versus Chaos.Current molecular biology reports · 2017Review
- Article
- Perception of the plant hormone ethylene: known-knowns and known-unknowns.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2016Review
- CB5C affects the glucosinolate profile in Arabidopsis thaliana.Plant signaling & behavior · 2016Article
- Maize and Arabidopsis ARGOS Proteins Interact with Ethylene Receptor Signaling Complex, Supporting a Regulatory Role for ARGOS in Ethylene Signal Transduction.Plant physiology · 2016Article
- Regulatory function of Arabidopsis lipid transfer protein 1 (LTP1) in ethylene response and signaling.Plant molecular biology · 2016Article
- Transgenic studies reveal the positive role of LeEIL-1 in regulating shikonin biosynthesis in Lithospermum erythrorhizon hairy roots.BMC plant biology · 2016Article
- Transgenic analysis reveals LeACS-1 as a positive regulator of ethylene-induced shikonin biosynthesis in Lithospermum erythrorhizon hairy roots.Plant molecular biology · 2016Article
- Genome-Wide Analysis of MicroRNA Responses to the Phytohormone Abscisic Acid in Populus euphratica.Frontiers in plant science · 2016Article
- Genome-wide identification and characterization of auxin response factor (ARF) family genes related to flower and fruit development in papaya (Carica papaya L.).BMC genomics · 2015Article
- Functional characterization of PhGR and PhGRL1 during flower senescence in the petunia.Plant cell reports · 2015Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Ethylene plays important roles in plant growth, development and stress responses, and is perceived by a family of receptors that repress ethylene responses when ethylene is absent. Repression by the ethylene receptor ETR1 depends on an integral membrane protein, REVERSION TO ETHYLENE SENSITIVITY1 (RTE1), which acts upstream of ETR1 in the endoplasmic reticulum (ER) membrane and Golgi apparatus. To investigate RTE1 function, we screened for RTE1-interacting proteins using the yeast split-ubiquitin assay, which yielded the ER-localized cytochrome b(5) (Cb5) isoform D. Cb5s are small hemoproteins that perform electron transfer reactions in all eukaryotes, but their roles in plants are relatively uncharacterized. Using bimolecular fluorescence complementation (BiFC), we found that all four ER-localized Arabidopsis Cb5 isoforms (AtCb5–B, -C, -D and -E) interact with RTE1 in plant cells. In support of this interaction, atcb5 mutants exhibited phenotypic parallels with rte1 mutants in Arabidopsis. Phenotypes included partial suppression of etr1–2 ethylene insensitivity, and no suppression of RTE1-independent ethylene receptor isoforms. The single loss-of-function mutants atcb5–b, -c and -d appeared similar to the wild-type, but double mutant combinations displayed slight ethylene hypersensitivity. Over-expression of AtCb5–D conferred reduced ethylene sensitivity similar to that conferred by RTE1 over-expression, and genetic analyses suggested that AtCb5–D acts upstream of RTE1 in the ethylene response. These findings suggest an unexpected role for Cb5, in which Cb5 and RTE1 are functional partners in promoting ETR1-mediated repression of ethylene signaling.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.