ArticleJournal of consulting and clinical psychology2014
What happens in treatment doesn't stay in treatment: cocaine abstinence during treatment is associated with fewer problems at follow-up.
Article in Journal of consulting and clinical psychology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- "I's" on the prize: A systematic review of individual differences in Contingency Management treatment response.Journal of substance abuse treatment · 2019Pooled it
- Systematic review of outcome domains and measures used in psychosocial and pharmacological treatment trials for cannabis use disorder.Drug and alcohol dependence · 2019Pooled it
- Randomized controlled trial of enhanced telephone monitoring with detoxification patients: 3- and 6-month outcomes.Journal of substance abuse treatment · 2019Trial
- Prompted to treatment by the criminal justice system: Relationships with treatment retention and outcome among cocaine users.The American journal on addictions · 2015Trial
- Smokers versus snorters: do treatment outcomes differ according to route of cocaine administration?Experimental and clinical psychopharmacology · 2013Trial
- Reduced drug use as an alternative valid outcome in individuals with stimulant use disorders: Findings from 13 multisite randomized clinical trials.Addiction (Abingdon, England) · 2024Article
- Exploring the performance of during-treatment substance use outcome measures in predicting longer-term psychosocial functioning and post-treatment abstinence.Drug and alcohol dependence · 2023Article
- Percentage of negative urine drug screens as a clinically meaningful endpoint for RCTs evaluating treatment for cocaine use.Drug and alcohol dependence · 2023Article
- Targeting white matter neuroprotection as a relapse prevention strategy for treatment of cocaine use disorder: Design of a mechanism-focused randomized clinical trial.Contemporary clinical trials · 2021Article
- Detecting change in psychiatric functioning in clinical trials for cocaine use disorder: sensitivity of the Addiction Severity Index and Brief Symptom Inventory.Drug and alcohol dependence · 2021Article
- Long-term functioning to provide empirical support for the clinical relevance of treatment outcomes for methamphetamine use disorders.Journal of substance abuse treatment · 2021Article
- Within-treatment frequency of use versus abstinence as a predictor of longitudinal post-treatment follow-up assessments of drug use.Drug and alcohol dependence · 2020Article
- Clinical validation of reduction in cocaine frequency level as an endpoint in clinical trials for cocaine use disorder.Drug and alcohol dependence · 2019Article
- Patterns of Cocaine Use During Treatment: Associations With Baseline Characteristics and Follow-Up Functioning.Journal of studies on alcohol and drugs · 2019Article
- Short and long-term improvements in psychiatric symptomatology to validate clinically meaningful treatment outcomes for cocaine use disorders.Drug and alcohol dependence · 2019Article
- What defines a clinically meaningful outcome in the treatment of substance use disorders: reductions in direct consequences of drug use or improvement in overall functioning?Addiction (Abingdon, England) · 2019Article
- Initial validation of a proxy indicator of functioning as a potential tool for establishing a clinically meaningful cocaine use outcome.Drug and alcohol dependence · 2017Article
- Examining Risk for Frequent Cocaine Use: Focus on an African American Treatment Population.Substance use & misuse · 2016Article
- Measures of outcome for stimulant trials: ACTTION recommendations and research agenda.Drug and alcohol dependence · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveCocaine users often present to treatment with a multitude of problems typically considered addiction related; however, there is little evidence that reductions in cocaine use are followed by reductions in these problems. This study evaluated the relationship between rates of cocaine use during treatment and the level of non-cocaine life problems experienced during a 12-month period following treatment in a pooled sample of 434 cocaine-dependent individuals participating in 1 of 5 randomized controlled trials.
methodStructural equation modeling and latent growth curve modeling were used to evaluate the relationship between frequency of cocaine use within treatment (8 or 12 weeks) and a latent construct of global problems indicated by the days of problems reported on the Addiction Severity Index across follow-up time points (1, 3, 6, and 12 months after treatment).
resultsBoth a continuous latent cocaine use outcome measure (percent days abstinent, percent positive urines, and maximum days of consecutive abstinence) and a dichotomous measure of cocaine use (≥21 consecutive days of abstinence) during the treatment period were associated with frequency of cocaine use and global problems during follow-up. Overall, results indicated that greater cocaine abstinence during the treatment period was associated with higher rates of abstinence and fewer global problems experienced following treatment.
conclusionThis is one of the first studies to support a model that suggests addiction-related problems decrease in accordance with achieving abstinence from cocaine, thereby providing evidence that within-treatment cocaine abstinence has benefits that extend beyond the frequency of drug use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.