ArticleTissue engineering. Part C, Methods2014
A surface-modified poly(ɛ-caprolactone) scaffold comprising variable nanosized surface-roughness using a plasma treatment.
Article in Tissue engineering. Part C, Methods, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Scaffold Design: A Review of Material and Immune Modulation in Bone Tissue Engineering.Cell and tissue banking · 2026Review
- eSolubilized amniotic membrane ECM as a promising biological surface treatment approach for 3D-printed bone tissue engineering scaffolds.Scientific reports · 2025Article
- Melt-Extrusion Additive Manufacturing for Tissue Engineering: Applications and Limitations.3D printing and additive manufacturing · 2025Article
- Article
- Polycaprolactone in Bone Tissue Engineering: A Comprehensive Review of Innovations in Scaffold Fabrication and Surface Modifications.Journal of functional biomaterials · 2024Review
- Mineral trioxide aggregate in membrane form as a barrier membrane in guided bone regeneration.Journal of dental sciences · 2024Article
- Poly-ε-Caprolactone 3D-Printed Porous Scaffold in a Femoral Condyle Defect Model Induces Early Osteo-Regeneration.Polymers · 2023Article
- Article
- 3D printing of bio-instructive materials: Toward directing the cell.Bioactive materials · 2023Article
- Crystal Growth of 3D Poly(ε-caprolactone) Based Bone Scaffolds and Its Effects on the Physical Properties and Cellular Interactions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Challenges of Periodontal Tissue Engineering: Increasing Biomimicry through 3D Printing and Controlled Dynamic Environment.Nanomaterials (Basel, Switzerland) · 2022Review
- Blood-Vessel-Inspired Hierarchical Trilayer Scaffolds: PCL/Gelatin-Driven Protein Adsorption and Cellular Interaction.Polymers · 2022Article
- Surface Roughness and Biocompatibility of Polycaprolactone Bone Scaffolds: An Energy-Density-Guided Parameter Optimization for Selective Laser Sintering.Frontiers in bioengineering and biotechnology · 2022Article
- Article
- Facile modification of polycaprolactone nanofibers with egg white protein.Journal of materials science. Materials in medicine · 2021Article
- Atmospheric Pressure Plasma Surface Treatment of Polymers and Influence on Cell Cultivation.Molecules (Basel, Switzerland) · 2021Review
- Biocompatible Electrospun Polycaprolactone-Polyaniline Scaffold Treated with Atmospheric Plasma to Improve Hydrophilicity.Bioengineering (Basel, Switzerland) · 2021Article
- Tuning Cell Behavior on 3D Scaffolds Fabricated by Atmospheric Plasma-Assisted Additive Manufacturing.ACS applied materials & interfaces · 2021Article
- 3D Printing Technologies in Metallic Implants: A Thematic Review on the Techniques and Procedures.International journal of bioprinting · 2021Review
- High Nanodiamond Content-PCL Composite for Tissue Engineering Scaffolds.Nanomaterials (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melt-plotted poly (ɛ-caprolactone) (PCL) has been widely applied in various tissue regenerations. However, its hydrophobic nature has hindered its usage in wider tissue engineering applications. In this study, we present the development of a porous and multilayered PCL scaffold, which shows outstanding hydrophilic properties and has a roughened surface consisting of homogeneously distributed nanosized pits. The scaffold was obtained using an innovative oxygen plasma treatment. This technology can induce variable nanoscale surface roughness, which is difficult from traditional plasma treatment. Osteoblast-like cells were cultured on the scaffolds and several cellular responses (cell viability, fluorescence images [live/dead cells, nucleus, and actin cytoskeleton], ALP activity, and calcium mineralization) were assessed for untreated PCL and conventionally plasma-treated PCL scaffolds. The data indicated that an appropriate roughness (654 ± 91 nm) of the PCL scaffold processed with the new plasma treatment induced more advantageous responses for the cells, compared with untreated scaffolds and traditional plasma-treated scaffolds.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.