ReviewFrontiers in cellular and infection microbiology2014
Shifting the paradigm from pathogens to pathobiome: new concepts in the light of meta-omics.
Review in Frontiers in cellular and infection microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
147 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Plant-parasitic nematode research in the arid desert landscape: a systematic review of challenges and bridging interventions.Frontiers in plant science · 2024Pooled it
- Sex-Biased Interactions Between Spur-Thighed Tortoises (Ecology and evolution · 2026Article
- Beyond the gut microbe: Rethinking infection, microbiome harmony, and the one-health continuum.World journal of gastrointestinal pharmacology and therapeutics · 2026Review
- Review
- Rhizosphere Microbiome Dynamics Associated with Root Rot inMicroorganisms · 2026Article
- Beyond detection: unveiling microbial dynamics in oak seedlings using fungal isolation and amplicon sequencing.Environmental microbiome · 2026Article
- Empowering One Health with metagenomics.One health outlook · 2026Review
- Soil as a Battlefield and a Reservoir: Linking Soil Components to the Epidemiology of Soilborne Plant Diseases.Microbial ecology · 2026Review
- Beyond Koch's postulates: the pathobiome paradigm in grapevine esca disease.FEMS microbiology ecology · 2026Review
- Exploring the functional microbiome of pigs within the porcine respiratory disease complex: viral-bacterial co-infections and virulence factor profiling.Microbiology spectrum · 2026Article
- The bacterial community composition of American Lobster (Homarus americanus) embryos and recently hatched larvae held under experimental laboratory conditions.Scientific reports · 2026Article
- Bacterial disease in seaweed aquaculture: pathogen diversity and future solutions.Journal of applied phycology · 2026Review
- Infection-driven proliferative phase impairment in chronic wounds: a mechanistic framework for precision regenerative therapy.Frontiers in immunology · 2026Review
- Multi-omics analysis reveals the pathobiome-host interactions in the bleaching disease of the seaweed Saccharina japonica.Microbiome · 2025Article
- The anti-inflammatory drug celecoxib is metabolized by Pseudomonas aeruginosa CYP107S1 in vitro and in vivo.Drug metabolism and disposition: the biological fate of chemicals · 2025Article
- Microbial Imbalance and Stochastic Assembly Drive Gut Dysbiosis in White-Gill DiseasedMicroorganisms · 2025Article
- A new scenario of pathogen-microbiota interactions involving the oomycete Plasmopara viticola.FEMS microbiology ecology · 2025Article
- Functional dynamics reveal the response of the crabapple (mSystems · 2025Article
- Holobiont-holobiont interactions across host-ectoparasite systems.Parasites & vectors · 2025Review
- A Study on the Changing Law of Bacterial Communities in the Milk of Bactrian Camels with Subclinical Mastitis.Microorganisms · 2025Article
87 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The concept of pathogenesis has evolved considerably over recent years, and the scenario "a microbe + virulence factors = disease" is probably far from reality in a number of cases. Actual pathogens have extremely broad biological diversity and are found in all major groups of microorganisms (viruses, bacteria, fungi, protozoa…). Their pathogenicity results from strong and often highly specific interactions they have with either their microbial environment, hosts and/or arthropod vectors. In this review, we explore the contribution of metagenomic approaches toward understanding pathogens within the context of microbial communities. With this broader view, we discussed the concept of "pathobiome" and the research questions that this raises.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.