Evidence map›Paper›PMID 24634715›Full record

ArticleThe journal of physical chemistry letters2014

Solvent-Exposed Salt Bridges Influence the Kinetics of α-Helix Folding and Unfolding.

Heleen Meuzelaar, Martijn Tros, Adriana Huerta-Viga, Chris N van Dijk, Jocelyne Vreede, Sander Woutersen

Abstract read
In one paragraph

Article in The journal of physical chemistry letters, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Deciphering the folding code of collagens.Nature communications · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Hydrophobic Collapse in N-Methylacetamide-Water Mixtures.The journal of physical chemistry. A · 2018
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Free energy landscape of a minimalist salt bridge model.Protein science : a publication of the Protein Society · 2016
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Heleen MeuzelaarVan 't Hoff Institute for Molecular Sciences, University of Amsterdam , Science Park 904, 1098 XH Amsterdam, The Netherlands.
Martijn TrosVan 't Hoff Institute for Molecular Sciences, University of Amsterdam , Science Park 904, 1098 XH Amsterdam, The Netherlands.
Adriana Huerta-VigaVan 't Hoff Institute for Molecular Sciences, University of Amsterdam , Science Park 904, 1098 XH Amsterdam, The Netherlands.
Chris N van DijkVan 't Hoff Institute for Molecular Sciences, University of Amsterdam , Science Park 904, 1098 XH Amsterdam, The Netherlands.
Jocelyne VreedeVan 't Hoff Institute for Molecular Sciences, University of Amsterdam , Science Park 904, 1098 XH Amsterdam, The Netherlands.
Sander WoutersenVan 't Hoff Institute for Molecular Sciences, University of Amsterdam , Science Park 904, 1098 XH Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salt bridges are known to play an essential role in the thermodynamic stability of the folded conformation of many proteins, but their influence on the

Identifiers

PMID24634715
PMCPMC3948500

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.