ReviewJournal of experimental zoology. Part B, Molecular and developmental evolution2014
Tetrahymena thermophila: a divergent perspective on membrane traffic.
Review in Journal of experimental zoology. Part B, Molecular and developmental evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Mechanism of Growth Phase-Dependent Nanoplastic Bioaccumulation inAntioxidants (Basel, Switzerland) · 2025Article
- Anterior-posterior pattern formation in ciliates.The Journal of eukaryotic microbiology · 2022Review
- Phagocytic and pinocytic uptake of cholesterol in Tetrahymena thermophila impact differently on gene regulation for sterol homeostasis.Scientific reports · 2021Article
- The Trypanosome Exocyst: A Conserved Structure Revealing a New Role in Endocytosis.PLoS pathogens · 2017Article
- Whole Genome Sequencing Identifies a Novel Factor Required for Secretory Granule Maturation in Tetrahymena thermophila.G3 (Bethesda, Md.) · 2016Article
- Review
- Resolving the homology-function relationship through comparative genomics of membrane-trafficking machinery and parasite cell biology.Molecular and biochemical parasitologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Tetrahymena thermophila, a member of the Ciliates, represents a class of organisms distantly related from commonly used model organisms in cell biology, and thus offers an opportunity to explore potentially novel mechanisms and their evolution. Ciliates, like all eukaryotes, possess a complex network of organelles that facilitate both macromolecular uptake and secretion. The underlying endocytic and exocytic pathways are key mediators of a cell's interaction with its environment, and may therefore show niche-specific adaptations. Our laboratory has taken a variety of approaches to identify key molecular determinants for membrane trafficking pathways in Tetrahymena. Studies of Rab GTPases, dynamins, and sortilin-family receptors substantiate the widespread conservation of some features but also uncover surprising roles for lineage-restricted innovation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.