ArticleScientific reports2014
Sequentially hetero-functional, topological polymers by step-growth thiol-yne approach.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- UV-cure hydrogels for cardiac regeneration: a comprehensive review.Stem cell research & therapy · 2025Review
- Review
- Polymer Nanocomposites via Click Chemistry Reactions.Polymers · 2017Review
- Triazine-Based Sequence-Defined Polymers with Side-Chain Diversity and Backbone-Backbone Interaction Motifs.Angewandte Chemie (International ed. in English) · 2016Article
- Synthesis of sequence-defined acrylate oligomersChemical science · 2015Article
- Synthesis of a library of propargylated and PEGylated α-hydroxy acids toward "clickable" polylactides via hydrolysis of cyanohydrin derivatives.The Journal of organic chemistry · 2014Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sequence-controlled polymers (SCPs) such as DNA and proteins play an important role in biology. Many efforts have been devoted to synthesize SCPs in the past half a century. However, to our knowledge, the artificial sequences containing independently functional groups have never been reported. Here, we present a facile and scalable approach based on radical-initiated step-growth polymerization to synthesize sequence-controlled functional polymers (SCFPs) with various topologies, covering from linear to random and hyperbranched polymers. The functional groups, such as OH/NH2, OH/COOH, and NH2/N3, alternately arranged along the chain, which were further selectively functionalized to achieve DNA-mimic and hetero-multifunctional SCPs. This user-friendly strategy exhibits advantages of commercially available monomers, catalyst-free process, fast reaction, high yield and water solvent, opening a general approach to facile and scalable synthesis of SCFPs.
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