Evidence map›Paper›PMID 24632990›Full record

GuidelineAlzheimer disease and associated disorders

Diagnostic criteria for vascular cognitive disorders: a VASCOG statement.

Perminder Sachdev, Raj Kalaria, John O'Brien, Ingmar Skoog, Suvarna Alladi, Sandra E Black, Deborah Blacker, Dan G Blazer, Christopher Chen, Helena Chui and 10 more

Open access · greenAbstract readPractice Guideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Alzheimer disease and associated disorders. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 406 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
406citing papers in PubMed, 9 pooled it
22.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

406 citing papers in PubMed, 9 syntheses or guidelines pooled it, 769 citations in OpenAlex.

  1. Pooled it
  2. Efficacy and safety ofFrontiers in pharmacology · 2026
    Pooled it
  3. Practical Brain MRI Guidelines for Anti-Aβ Antibody Treatment in Early Symptomatic Alzheimer's Disease.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
    Guideline
  4. Visual field defects in dementia: A scoping review.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Pooled it
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346 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 9 institutions in 5 countries.

Perminder Sachdev*Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales †Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, NSW, Australia ‡Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, Tyne and Wear §Department of Psychiatry, University of Cambridge, Cambridge, UK ∥Department of Psychiatry and Neurochemistry, University of Gothenburg, Göteborg, Sweden ¶Department of Neurology, Nizam's Institute of Medical Sciences, Hyderabad, India #University of Toronto and Sunnybrook Health Sciences Centre, Toronto, ON §§§Dalhousie University, Halifax, NS, Canada **Departments of Epidemiology, Harvard Medical School, Boston, MA ††Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC ‡‡Memory Aging and Cognition Centre, National University Health System, Singapore §§Department of Neurology, University of Southern California and Keck School of Medicine, Los Angeles, CA ∥∥University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, PA ¶¶Institute of Clinical Neurobiology, Vienna, Austria ##Department of Psychiatry, University of California, San Diego, CA ***University Lille Nord de France UDSL and Memory Clinic, CHU, Lille, France †††The Carver College of Medicine, The University of Iowa, Iowa City, IA ‡‡‡Alzheimer Centre and Department of Neurology, VU University Medical Centre, Amsterdam, The Netherlands ∥∥∥Methodist Neurological Institute, Houston, TX.
Raj Kalaria
John O'Brien
Ingmar Skoog
Suvarna Alladi
Sandra E Black
Deborah Blacker
Dan G Blazer
Christopher Chen
Helena Chui
Mary Ganguli
Kurt Jellinger
Dilip V Jeste
Florence Pasquier
Jane Paulsen
Niels Prins
Kenneth Rockwood
Gustavo Roman
Philip Scheltens
Internationlal Society for Vascular Behavioral and Cognitive Disorders
Newcastle University · GBPrince of Wales Hospital · AUUniversity of Cambridge · GBUniversity of Gothenburg · SENizam's Institute of Medical Sciences · INUNSW Sydney · AUHealth Sciences Centre · CASunnybrook Health Science Centre · CAUniversity of Newcastle Australia · AU

Funding

THE ROLE OF ADVANCED CAA IN ALZHEIMER'S DEMENTIAP50AG005134 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HYMAN, BRADLEY T. · 1985 to 2018
$42.1M
VASCULAR RISK AND COGNITIVE STATUS IN A LATINO POPULATIONP50AG005142 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ARANDA, MARIA P. · 1985 to 2019
$41.0M
Research Education ComponentP30AG062421 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Sudeshna Das · 2019 to 2026
$36.5M
Metabolic Effects of Newer Antipsychotics in Older PtsR01MH071536 · NIMH · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI JESTE, DILIP V. · 2005 to 2009
$4.8M
Epidemiology of Aging Brain and BehaviorK07AG044395 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GANGULI, MARY · 2013 to 2017
$615k
Medical Research Council G0400074Medical Research Council G0500247Medical Research Council G0502157Medical Research Council G0900652Medical Research Council G1100540Medical Research Council MR/L016451/1NIA NIH HHS K07 AG044395NIA NIH HHS P30 AG062421NIA NIH HHS P50 AG005134NIA NIH HHS P50 AG005142NIMH NIH HHS R01 MH071536
6 · The paper itself

Abstract

backgroundSeveral sets of diagnostic criteria have been published for vascular dementia since the 1960s. The continuing ambiguity in vascular dementia definition warrants a critical reexamination.

methodsParticipants at a special symposium of the International Society for Vascular Behavioral and Cognitive Disorders (VASCOG) in 2009 critiqued the current criteria. They drafted a proposal for a new set of criteria, later reviewed through multiple drafts by the group, including additional experts and the members of the Neurocognitive Disorders Work Group of the fifth revision of Diagnostic and Statistical Manual (DSM-5) Task Force.

resultsCognitive disorders of vascular etiology are a heterogeneous group of disorders with diverse pathologies and clinical manifestations, discussed broadly under the rubric of vascular cognitive disorders (VCD). The continuum of vascular cognitive impairment is recognized by the categories of Mild Vascular Cognitive Disorder, and Vascular Dementia or Major Vascular Cognitive Disorder. Diagnostic thresholds are defined. Clinical and neuroimaging criteria are proposed for establishing vascular etiology. Subtypes of VCD are described, and the frequent cooccurrence of Alzheimer disease pathology emphasized.

conclusionsThe proposed criteria for VCD provide a coherent approach to the diagnosis of this diverse group of disorders, with a view to stimulating clinical and pathologic validation studies. These criteria can be harmonized with the DSM-5 criteria such that an international consensus on the criteria for VCD may be achieved.

Indexed as

Cognition DisordersDementia, VascularHumans

Identifiers

PMID24632990
PMCPMC4139434
OpenAlexW2035892177

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.