ArticleScientific reports2014
Near-infrared fluorescence imaging of cancer cells and tumors through specific biosynthesis of silver nanoclusters.
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Atomic Simulation of the Coalescence and Melting Process of AgNanomaterials (Basel, Switzerland) · 2026Article
- Construction of hyperbranched polylysine-modified antibacterial polyurethane foam dressings and their promotion of infected deep burn wound healing.Regenerative biomaterials · 2026Article
- Paradoxical Features Empower Biogenic Silver Nanoparticles.Molecules (Basel, Switzerland) · 2025Review
- Highly emissive dibenzofuranfluorophores with aggregation-induced emission for bioimaging in HeLa cell lines.RSC advances · 2025Article
- DNA Nanoribbon-Assisted Intracellular Biosynthesis of Fluorescent Gold Nanoclusters for Cancer Cell Imaging.JACS Au · 2023Article
- Tracking tumor heterogeneity and progression with near-infrared II fluorophores.Exploration (Beijing, China) · 2023Review
- Slow degrading Mg-based materials induce tumor cell dormancy on an osteosarcoma-fibroblast coculture model.Bioactive materials · 2022Article
- Tumor-targeting inorganic nanomaterials synthesized by living cells.Nanoscale advances · 2021Review
- Synergistic integration of metal nanoclusters and biomolecules as hybrid systems for therapeutic applications.Acta pharmaceutica Sinica. B · 2021Review
- Direct Laser Writing of Fluorescent Silver Nanoclusters: A Review of Methods and Applications.ACS applied nano materials · 2020Article
- Human Nontumorigenic Microglia Synthesize Strongly Fluorescent Au/Fe Nanoclusters, Retaining Bioavailability.ACS omega · 2020Article
- Optimizing an Osteosarcoma-Fibroblast Coculture Model to Study Antitumoral Activity of Magnesium-Based Biomaterials.International journal of molecular sciences · 2020Article
- In Vivo Biosynthesis of Inorganic Nanomaterials Using Eukaryotes-A Review.Molecules (Basel, Switzerland) · 2020Review
- Differential Interaction of Metal Ions with Gold Nanoclusters and Application in Detection of Cobalt and Cadmium.Journal of fluorescence · 2020Article
- Augmented interaction of multivalent arginine coated gold nanoclusters with lipid membranes and cells.RSC advances · 2020Article
- Endogenous HiScience · 2019Article
- A multifunctional targeting probe with dual-mode imaging and photothermal therapy used in vivo.Journal of nanobiotechnology · 2018Article
- Optical molecular imaging for tumor detection and image-guided surgery.Biomaterials · 2018Review
- Fluorescence enhancement of gold nanoclustersRSC advances · 2018Article
- Metallic Nanoclusters for Cancer Imaging and Therapy.Current medicinal chemistry · 2018Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human life toll by cancer, one of the highest among most dreaded diseases in advanced societies, could be reduced by implementing evidence-based strategies for its prevention, early diagnosis and assessment of the progress and suitability of therapies by fast and non-invasive methods. In this contribution, a novel strategy is reported for highly sensitive recognition and in vivo imaging of cancer cells taking advantage of their spontaneous ability to generate silver nanoclusters (NCs) with high near-infrared fluorescence emission by intracellular reduction of innocuous silver salts. Both ex vivo experiments comparing cancer cell models to normal cells and in vivo imaging of subcutaneous xenografted tumor (cervical carcinoma model) in nude mice established the validity of this strategy for precise and selective imaging of cells and tumors. Furthermore, it was observed that the spontaneous self-generation of Ag NCs by tumors in their inside led to drastic reduction of their sizes and often to complete remission, thus providing important hope for new therapy strategies based on cheap and readily available agents.
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