Evidence map›Paper›PMID 24632760›Full record

Trial reportPsychiatric services (Washington, D.C.)2014

Early intervention to preempt major depression among older black and white adults.

Charles F Reynolds, Stephen B Thomas, Jennifer Q Morse, Stewart J Anderson, Steven Albert, Mary Amanda Dew, Amy Begley, Jordan F Karp, Ariel Gildengers, Meryl A Butters and 4 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Psychiatric services (Washington, D.C.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
10.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 55 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Depression Agency-Based Collaborative: Effect of Problem-Solving Therapy on Risk of Common Mental Disorders in Older Adults With Home Care Needs.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2019
    Trial
  4. Trial
  5. Measuring Participant Effort in a Depression Prevention Trial: Who Engages in Problem-Solving Therapy?The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2017
    Trial
  6. Challenges and Solutions for Depression Prevention Research: Methodology for a Depression Prevention Trial for Older Adults with Knee Arthritis and Emotional Distress.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2016
    Trial
  7. Trial
  8. Improving health-related quality of life in older African American and non-Latino White patients.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2015
    Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Reimagining Resilience in Aging: Leveraging AI/ML, Big Data Analytics, and Systems Innovation.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025
    Article
  14. Major depressive disorder.Nature reviews. Disease primers · 2023
    Review
  15. Centering Culture in Mental Health: Differences in Diagnosis, Treatment, and Access to Care Among Older People of Color.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
    Review
  16. Article
  17. Coping strategies and depressive symptoms in cancer patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2020
    Observational
  18. Observational
  19. Review
  20. ¡HOLA, Amigos! Toward Preventing Anxiety and Depression in Older Latinos.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 2 countries.

Charles F Reynolds
Stephen B Thomas
Jennifer Q Morse
Stewart J Anderson
Steven Albert
Mary Amanda Dew
Amy Begley
Jordan F Karp
Ariel Gildengers
Meryl A Butters
Jacqueline A Stack
John Kasckow
Mark D Miller
Sandra C Quinn
University of Maryland, Baltimore · US

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI JENNIFER S BRACH · 2004 to 2026
$28.6M
RESEARCH TRAINING COREP60MD000207 · NIMHD · UNIV OF MARYLAND, COLLEGE PARK · PI THOMAS, STEPHEN B. · 2002 to 2011
$10.8M
RESEARCH METHODS COREP30MH090333 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEW, MARY AMANDA · 2011 to 2015
$8.3M
Uncovering and Addressing Cultural Beliefs Behind Vaccine Racial Disparities P20MD006737 · NIMHD · UNIV OF MARYLAND, COLLEGE PARK · PI QUINN, SANDRA CROUSE, THOMAS, STEPHEN B. · 2012 to 2016
$5.9M
The Effects of Bipolar Disorder and its Comorbidities on Cognition in Older AdultR01MH084921 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GILDENGERS, ARIEL GERARD · 2010 to 2014
$1.8M
NCATS NIH HHS UL1 TR000005NCATS NIH HHS UL1TR000005NCRR NIH HHS UL1 RR024153NCRR NIH HHS UL1RR024153NIA NIH HHS P30 AG024827NIMHD NIH HHS P20 MD006737NIMHD NIH HHS P60 MD000207NIMH NIH HHS P30 MH090333NIMH NIH HHS R01 MH084921
6 · The paper itself

Abstract

objectiveThe study objective was to assess the efficacy of problem-solving therapy for primary care (PST-PC) for preventing episodes of major depression and mitigating depressive symptoms of older black and white adults. The comparison group received dietary coaching.

methodsA total of 247 participants (90 blacks, 154 whites, and three Asians) with subsyndromal depressive symptoms were recruited into a randomized depression prevention trial that compared effects of individually delivered PST-PC and dietary coaching on time to major depressive episode and level of depressive symptoms (Beck Depression Inventory) over two years. Cumulative intervention time averaged 5.5-6.0 hours in each study arm.

resultsThe two groups did not differ significantly in time to major depressive episodes, and incidence of such episodes was low (blacks, N=8, 9%; whites, N=13, 8%), compared with published rates of 20%-25% over one year among persons with subsyndromal symptoms and receiving care as usual. Participants also showed a mean decrease of 4 points in depressive symptoms, sustained over two years. Despite greater burden of depression risk factors among blacks, no significant differences from whites were found in the primary outcome.

conclusionsBoth PST-PC and dietary coaching are potentially effective in protecting older black and white adults with subsyndromal depressive symptoms from developing episodes of major depression over two years. Absent a control for concurrent usual care, this conclusion is preliminary. If confirmed, both interventions hold promise as scalable, safe, nonstigmatizing interventions for delaying or preventing episodes of major depression in the nation's increasingly diverse older population.

Indexed as

Problem SolvingAgedBlack or African AmericanDepressionEarly Medical InterventionFemaleHumansMajor Depressive DisorderMaleMiddle AgedPrimary Health CarePsychotherapyTreatment OutcomeWhite People

Identifiers

PMID24632760
PMCPMC4050338
OpenAlexW2058796472

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.