Evidence map›Paper›PMID 24632722›Full record

ArticleScientific reports2014

Biocompatible and photostable AIE dots with red emission for in vivo two-photon bioimaging.

Dan Wang, Jun Qian, Wei Qin, Anjun Qin, Ben Zhong Tang, Sailing He

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 107 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Extracellular ASC exacerbated the recurrent ischemic stroke in an NLRP3-dependent manner.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Dan Wang1] Centre for Optical and Electromagnetic Research, Zhejiang Provincial Key Laboratory for Sensing Technologies, Joint Research Center of Photonics of the Royal Institute of Technology and Zhejiang University (JORCEP), Zhejiang University, Hangzhou 310058, China [2] State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing 100029, China [3].
Jun Qian1] Centre for Optical and Electromagnetic Research, Zhejiang Provincial Key Laboratory for Sensing Technologies, Joint Research Center of Photonics of the Royal Institute of Technology and Zhejiang University (JORCEP), Zhejiang University, Hangzhou 310058, China [2].
Wei QinDepartment of Chemistry, Division of Biomedical Engineering, and Institute for Advanced Study, The Hong Kong University of Science and Technology (HKUST), Clear Water Bay, Kowloon, Hong Kong, China.
Anjun QinMoE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China.
Ben Zhong Tang1] Department of Chemistry, Division of Biomedical Engineering, and Institute for Advanced Study, The Hong Kong University of Science and Technology (HKUST), Clear Water Bay, Kowloon, Hong Kong, China [2] Guangdong Innovative Research Team, SCUT-HKUST Joint Research Laboratory, State Key Laboratory of Luminescent Materials and Devices, South China University of Technology (SCUT), Guangzhou 510640, China.
Sailing HeCentre for Optical and Electromagnetic Research, Zhejiang Provincial Key Laboratory for Sensing Technologies, Joint Research Center of Photonics of the Royal Institute of Technology and Zhejiang University (JORCEP), Zhejiang University, Hangzhou 310058, China.
Zhejiang University of Technology · CNHong Kong University of Science and Technology · HKZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioimaging systems with cytocompatibility, photostability, red fluorescence, and optical nonlinearity are in great demand. Herein we report such a bioimaging system. Integration of tetraphenylethene (T), triphenylamine (T), and fumaronitrile (F) units yielded adduct TTF with aggregation-induced emission (AIE). Nanodots of the AIE fluorogen with efficient red emission were fabricated by encapsulating TTF with phospholipid. The AIE dots enabled three-dimensional dynamic imaging with high resolution in blood vessels of mouse brain under two-photon excitation.

Indexed as

PhotonsQuantum DotsAminesAnimalsBlood VesselsBrainDiagnostic ImagingDrug CarriersDrug CompoundingFluorescent DyesFumaratesMiceMicroscopy, Fluorescence, MultiphotonPolyethylenesTerphenyl CompoundsAminesDrug CarriersFluorescent DyesFumaratesfumaronitrilePolyethylenesTerphenyl Compounds

Identifiers

PMID24632722
PMCPMC3955920
OpenAlexW2025041938

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.