ArticleThe Plant cell2014
Systems analysis of auxin transport in the Arabidopsis root apex.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
107 citing papers in PubMed, 215 citations in OpenAlex.
- Dual ubiquitin signalling by SLOMO controls AUX1 activity and turnover during root gravitropism.The EMBO journal · 2026Article
- Natural Variations of ZmRLR1 Mediate the Root Lodging Resistance of Maize by Regulating Root Ascorbate and Auxin Homeostasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Polar-localized EXO70G1 regulates root development in Arabidopsis thaliana.Journal of integrative plant biology · 2026Article
- Hormonal regulation of root growth under moderately elevated temperatures.Annals of botany · 2025Review
- Computational modeling of plant root development: the art and the science.The New phytologist · 2025Review
- Modeling Arabidopsis root growth and development.Plant physiology · 2025Review
- Predictive genetic circuit design for phenotype reprogramming in plants.Nature communications · 2025Article
- Article
- The role of auxin transport through plasmodesmata in leaf vein canalization and patterning.Frontiers in plant science · 2025Article
- Multi-scale mechanisms driving root regeneration: From regeneration competence to tissue repatterning.The Plant journal : for cell and molecular biology · 2024Review
- Article
- A predictive model for ethylene-mediated auxin and cytokinin patterning in the Arabidopsis root.Plant communications · 2024Article
- ZmPILS6 is an auxin efflux carrier required for maize root morphogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
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- Article
- Multiscale Asymptotic Analysis Reveals How Cell Growth and Subcellular Compartments Affect Tissue-Scale Hormone Transport.Bulletin of mathematical biology · 2023Article
- Computer models of cell polarity establishment in plants.Plant physiology · 2023Review
- Article
- Gibberellin and abscisic acid transporters facilitate endodermal suberin formation in Arabidopsis.Nature plants · 2023Article
- Roles of very long-chain fatty acids in compound leaf patterning in Medicago truncatula.Plant physiology · 2023Article
47 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 6 institutions in 4 countries.
Funding
Abstract
Auxin is a key regulator of plant growth and development. Within the root tip, auxin distribution plays a crucial role specifying developmental zones and coordinating tropic responses. Determining how the organ-scale auxin pattern is regulated at the cellular scale is essential to understanding how these processes are controlled. In this study, we developed an auxin transport model based on actual root cell geometries and carrier subcellular localizations. We tested model predictions using the DII-VENUS auxin sensor in conjunction with state-of-the-art segmentation tools. Our study revealed that auxin efflux carriers alone cannot create the pattern of auxin distribution at the root tip and that AUX1/LAX influx carriers are also required. We observed that AUX1 in lateral root cap (LRC) and elongating epidermal cells greatly enhance auxin's shootward flux, with this flux being predominantly through the LRC, entering the epidermal cells only as they enter the elongation zone. We conclude that the nonpolar AUX1/LAX influx carriers control which tissues have high auxin levels, whereas the polar PIN carriers control the direction of auxin transport within these tissues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.