Evidence map›Paper›PMID 24632348›Full record

ReviewClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2014

Innate immunity in disease.

David E Elliott, Sana S Siddique, Joel V Weinstock

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
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  4. Article
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  7. Review
  8. New understanding on the pathogenesis of acute arterial thrombosis.Journal of geriatric cardiology : JGC · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

David E ElliottDivision of Gastroenterology/Hepatology, Department of Internal Medicine, University of Iowa, Iowa City, Iowa.
Sana S SiddiqueDivision of Gastroenterology-Hepatology, Department of Internal Medicine, Tufts Medical Center, Boston, Massachusetts.
Joel V WeinstockDivision of Gastroenterology-Hepatology, Department of Internal Medicine, Tufts Medical Center, Boston, Massachusetts. Electronic address: jweinstock2@tuftsmedicalcenter.org.
Tufts Medical Center · USUniversity of Iowa · US

Funding

Helminthic Protection From IBDR01DK058755 · NIDDK · UNIVERSITY OF IOWA · PI WEINSTOCK, JOEL VINCENT · 2001 to 2013
$4.1M
Induction of Regulatory T Cells to Control IBDR01DK091987 · NIDDK · TUFTS MEDICAL CENTER · PI WEINSTOCK, JOEL VINCENT · 2011 to 2014
$1.4M
Helminthic Protection From IBDR56DK058755 · NIDDK · TUFTS MEDICAL CENTER · PI WEINSTOCK, JOEL VINCENT · 2009 to 2009
$485k
NIDDK NIH HHS DK058755NIDDK NIH HHS DK091987NIDDK NIH HHS R01 DK058755NIDDK NIH HHS R01 DK091987NIDDK NIH HHS R56 DK058755
6 · The paper itself

Abstract

Cells can innately recognize generic products of viruses, bacteria, fungi, or injured tissue by engagement of pattern recognition receptors. Innate immune cells rapidly respond to this engagement to control commensals, thwart pathogens, and/or prompt repair. Insufficient or excessive activation of the innate immune response results in disease. This review focuses on pattern recognition receptors and cells of the innate immune system that are important for intestinal function. Our improving knowledge pertaining to this important aspect of our immune response is opening potential important new therapeutic opportunities for the treatment of disease.

Indexed as

Immunity, InnateCytokinesGastrointestinal DiseasesHumansLeukocytesReceptors, Pattern RecognitionCytokinesReceptors, Pattern RecognitionColitisGastroenterologyInnate ImmunityMucosa

Identifiers

PMID24632348
PMCPMC4083246
OpenAlexW2105866537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.