ArticleThe EMBO journal2014
Fetal cannabinoid receptors and the "dis-joint-ed" brain.
Article in The EMBO journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07456579 (Assessment of Alcohol and Cannabis Use Among Pregnant Women in Slovenia and Meconium Microbiome Analysis of Positive Samples), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Alcohol and Cannabis Use Among Pregnant Women in Slovenia and Meconium Microbiome Analysis of Positive Samples
Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Prenatal Cannabis Use and Neonatal Outcomes: A Systematic Review and Meta-Analysis.JAMA pediatrics · 2025Article
- Prenatal delta-9-tetrahydrocannabinol exposure alters fetal neurodevelopment in rhesus macaques.Scientific reports · 2024Article
- Article
- Prenatal delta-9-tetrahydrocannabinol exposure is associated with changes in rhesus macaque DNA methylation enriched for autism genes.Clinical epigenetics · 2023Article
- An epigenetic synopsis of parental substance use.Epigenomics · 2023Review
- Intrauterine cannabis exposure and fetal and maternal blood flow: a case-control study.Acta obstetricia et gynecologica Scandinavica · 2022Article
- Impact of cannabinoids on pregnancy, reproductive health, and offspring outcomes.American journal of obstetrics and gynecology · 2022Review
- Neonatal Intensive Care Unit Network Neurobehavioral Scale Profiles in Full-Term Infants: Associations with Maternal Adversity, Medical Risk, and Neonatal Outcomes.The Journal of pediatrics · 2022Observational
- Marijuana Use in Pregnancy: A Review.Obstetrical & gynecological survey · 2019Review
- Cannabis use during pregnancy: Pharmacokinetics and effects on child development.Pharmacology & therapeutics · 2018Review
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microtubule turnover in the growing axons is required for directional axonal growth and synapse formation in the developing brain. In this issue of The EMBO Journal, Tortoriello et al (2014) show that the microtubule-binding protein SCG10/stathmin-2 is a specific molecular target for a CB1 receptor-mediated effect of Δ(9)-tetrahydrocannabinol (THC), the psychoactive ingredient of smoked marijuana, in the fetal brain. Considering the role of CB1 in modulating the specification and long-distance migration of neurons in the perinatal brain, this study reveals an interesting mechanism potentially accounting for connectivity deficits during cortical development following exposure to CB1 agonists or THC during pregnancy.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.