ArticleJournal of infection and public health
Prevalence and risk factors for antibiotic-resistant community-associated bloodstream infections.
Article in Journal of infection and public health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk factors for antibiotic resistance development in healthcare settings in China: a systematic review.Epidemiology and infection · 2021Pooled it
- High proportions of multidrug-resistant Klebsiella pneumoniae isolates in community-acquired infections, Brazil.Scientific reports · 2025Article
- Aerobic bacteria study, clinical spectrum, and outcome of patients with community-acquired multidrug-resistant pathogens.Journal of family medicine and primary care · 2024Article
- Prevalence and Potential Risk Factors for the Acquisition of Antibiotic-ResistantBioMed research international · 2023Article
- Analysis of infections among patients with historical culture positive for extended-spectrum beta-lactamase (ESBL)-producingAntimicrobial stewardship & healthcare epidemiology : ASHE · 2023Article
- Risk factors for nosocomial bloodstream infections in COVID-19 affected patients: protocol for a case-control study.European journal of hospital pharmacy : science and practice · 2022Article
- Multidrug-Resistant Bacteria: Their Mechanism of Action and Prophylaxis.BioMed research international · 2022Review
- Improved diagnostic prediction of the pathogenicity of bloodstream isolates of Staphylococcus epidermidis.PloS one · 2021Article
- Multidrug-Resistant Bacteria in the Community: An Update.Infectious disease clinics of North America · 2020Review
- Bacterial resistance to antibiotics and associated factors in two hospital centers in Lebanon from January 2017 to June 2017.Infection prevention in practice · 2020Article
- Clinical and microbiological characteristics and outcomes of community-acquired sepsis among adults: a single center, 1-year retrospective observational cohort study from Hungary.BMC infectious diseases · 2019Observational
- Self-medication of antibiotics: investigating practice among university students at the Malaysian National Defence University.Infection and drug resistance · 2019Article
- Multidrug-Resistant Bacteria in the Community: Trends and Lessons Learned.Infectious disease clinics of North America · 2016Review
- Bacteremia in Early Infancy: Etiology and Management.Current infectious disease reports · 2016Article
- The Impact of Restricting Over-the-Counter Sales of Antimicrobial Drugs: Preliminary Analysis of National Data.Medicine · 2015Observational
- Challenges Associated With Using Large Data Sets for Quality Assessment and Research in Clinical Settings.Policy, politics & nursing practice · 2015Review
- Gram-negative bacteria as emerging pathogens affecting mortality in skin and soft tissue infections.HippokratiaArticle
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3 authors.
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Abstract
backgroundAntibiotic resistance is increasing in many community settings. The purpose of this study was to determine the proportion of antibiotic resistant community-associated bloodstream infections (CA-BSIs) present on hospital admissions to identify risk factors for acquiring resistant versus susceptible CA-BSIs and to describe the incidence of concurrent infections with CA-BSIs.
methodsWe conducted a retrospective cohort study of patients discharged from one community, one pediatric, and two tertiary/quaternary care hospitals within an academically affiliated network in the borough of Manhattan in New York, NY, from 2006 to 2008. The CA-BSIs present at hospital admission were defined as BSIs occurring within the first 48h of hospitalization. Infections and patient characteristics were identified using data available from patients' electronic medical records and discharge records.
resultsIn total, 1677 CA-BSIs were identified. Staphylococcus aureus had the largest proportion of resistance (41.2%), followed by enterococcal species (24.3%), Pseudomonas aeruginosa (20.2%), Streptococcus pneumoniae (16.6%), Acinetobacter baumannii (10.0%), and Klebsiella pneumoniae (9.9%). Significant predictors of resistance were prior residence in a skilled nursing facility (OR, 2.55; 95% CI, 1.39-4.70), advanced age (1.01; 1.002-1.02), presence of malignancy (0.58; 0.37-0.91), prior hospitalization (1.62; 1.17-2.23), a weighted Charlson score (1.09; 1.02-1.17) for S. aureus, presence of malignancy (1.82; 1.004-3.30), prior hospitalizations (2.03; 1.12-3.38) for enterococcal species, and younger age for S. pneumoniae (p=0.02). Urinary tract infections were the most common concurrent infection (n=45/87, 51.7%).
conclusionOver 27% of the CA-BSIs present on admission were antibiotic resistant. Understanding the prevalence and risk factors for CA-BSIs may help improve empiric antibiotic therapy and outcomes for patients with community-onset infections.
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